DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Burs and BMPER

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	NP_001352237.1	Gene:	BMPER / 168667	HGNCID:	24154	Length:	685	Species:	Homo sapiens

Alignment Length:	186	Identity:	45/186 - (24%)
Similarity:	59/186 - (31%)	Gaps:	66/186 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 VLILLYCVLVSILKLCTAQPDSSVAATDNDITHLGDDCQVTPVIHVLQYPGCVPKPIPSFACVGR 79
            ||:||.|..|. :.|.::....|||..:|:    |:         |||.|.....|.....|:.:
Human    25 VLLLLNCSGVP-MSLASSFLTGSVAKCENE----GE---------VLQIPFITDNPCIMCVCLNK 75

  Fly    80 ---------------CASYIQVSG------------------SKIWQM-ERSCMC--CQESGERE 108
                           ||..|:..|                  |..||. ...|:.  |||....|
Human    76 EVTCKREKCPVLSRDCALAIKQRGACCEQCKGCTYEGNTYNSSFKWQSPAEPCVLRQCQEGVVTE 140

  Fly   109 AAVSLFCPKVKPGERKFKKVLTKAPLE--CMCRP-CTSIEESGIIPQEIAGYSDEG 161
            :.|...             |..|.|||  .||.| |......|:..||...:..||
Human   141 SGVRCV-------------VHCKNPLEHLGMCCPTCPGCVFEGVQYQEGEEFQPEG 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	24/125 (19%)
BMPER	NP_001352237.1	VWC	166..224	CDD:278520	5/18 (28%)
		VWC	301..357	CDD:327433
		VWD	364..508	CDD:306577
		C8	560..624	CDD:312319
		TIL	629..682	CDD:307783
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900