DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Burs and gja8

DIOPT Version :9

Sequence 1:	NP_650983.1	Gene:	Burs / 42560	FlyBaseID:	FBgn0038901	Length:	173	Species:	Drosophila melanogaster
Sequence 2:	XP_004918275.1	Gene:	gja8 / 100490617	XenbaseID:	XB-GENE-493230	Length:	593	Species:	Xenopus tropicalis

Alignment Length:	160	Identity:	35/160 - (21%)
Similarity:	51/160 - (31%)	Gaps:	58/160 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 RHENNKVFVLILLYCVLVSILKLCTAQPDSSVAATDNDITHLG-DDCQVT---PVIHVLQYPGCV 67
            |.....:|:..:|....||:.....            :|:||| ...::.   |..|..|.||.|
Frog   205 RPTEKTIFITFMLAVAAVSLFLNVV------------EISHLGWKKIRLAFRRPDQHPQQLPGEV 257

  Fly    68 -PKPIPSFACVGRCASYIQVSGSKIWQMERSCMCCQESGEREAAVSLFCPKVKPGERKFKKVLTK 131
             .|.:.|.|    .:|..:..|.|:.             :.|..||.|.|..:.|       |..
Frog   258 SQKSLHSIA----ISSIPKSKGYKLL-------------DEEKVVSRFYPMTEVG-------LEA 298

  Fly   132 APLECMCRPCTSIEESGIIPQEIAGYSDEG 161
            :||                |....|| |:|
Frog   299 SPL----------------PAHFNGY-DKG 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Burs	NP_650983.1	GHB_like	50..138	CDD:419725	21/91 (23%)
gja8	XP_004918275.1	Connexin	3..236	CDD:365820	8/42 (19%)
		Connexin50	270..332	CDD:367533	16/79 (20%)
		PRK07764	<333..554	CDD:236090
		Connexin40_C	<563..593	CDD:374805
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1216
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900