Protein Alignment CG42335 and pepN

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_415452.1
• Gene: pepN / 947253
• ECOCYCID: EG10696
• Length: 870
• Species: Escherichia coli
• Alignment Length: 861
• Identity: 182/861 - (21%)
• Similarity: 294/861 - (34%)
• Gaps: 253/861 - (29%)

  Fly   160 TQMQRINARLVLPCFDEPALKAQFQLQIVR---------PNGYQSIANTKLKETKALSQDRFVDH 215
            ||.:....|.:....|.|.:.|:|..:|:.         .|| ..:|..:|:..:...|  :.|.
E. coli   118 TQCEAEGFRHITYYLDRPDVLARFTTKIIADKIKYPFLLSNG-NRVAQGELENGRHWVQ--WQDP 179

  Fly   216 FKETPVMSTYLLAFMVANYSARGNESEFAVLTRPEFYDNTEFSYHVGQQVVSAYGELFQSPYA-- 278
            |.:    ..||.|.:.         .:|.|| |..|  .|.....|..::....|.|.::|:|
E. coli   180 FPK----PCYLFALVA---------GDFDVL-RDTF--TTRSGREVALELYVDRGNLDRAPWAMT 228

  Fly   279 ---------------ELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEF-- 326
                           |...|:....:...|....|||.||.|::...::..   :|..:||::
E. coli   229 SLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYVLAR---TDTATDKDYLD 290

  Fly   327 AIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFV---------- 381
            ..|:|.||..|.|.|:.||...|....|.|....:              .|::|.
E. coli   291 IERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVF--------------RDQEFSSDLGSRAVNR 341

  Fly   382 ---VRQMQ-LIFGTDAQNGTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFD 442
               ||.|: |.|..||.....|: .|:..|:..:    .::...|.|||.::||...|:|.|||.
E. coli   342 INNVRTMRGLQFAEDASPMAHPI-RPDMVIEMNN----FYTLTVYEKGAEVIRMIHTLLGEENFQ 401

  Fly   443 TAIRSYLQQYHLTNTVPYNLFYHLFEHWPKNQDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTV 507
            ..::.|.:: |..:....:.|....|   ...:|||..|...|::            .|..:|||
E. coli   402 KGMQLYFER-HDGSAATCDDFVQAME---DASNVDLSHFRRWYSQ------------SGTPIVTV 450

  Fly   508 EQSRFLLNKDDGSNATLKYTVPITFTTNLERDFYNLTPYKYLHKTVNVLWLDFTSPIDWILFNLR 572
                    |||.:..|.:||:.|:..|....|.....|   ||                |.|.:.
E. coli   451 --------KDDYNPETEQYTLTISQRTPATPDQAEKQP---LH----------------IPFAIE 488

  Fly   573 QSNYQRVFYDDTLREGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKE 637
                   .||:   ||.:          ||::.....::.:.|..||:..          ::...
E. coli   489 -------LYDN---EGKV----------IPLQKGGHPVNSVLNVTQAEQT----------FVFDN 523

  Fly   638 VEYVPWYAVYENLNTVAK---RLTPEQLP--------DF-RIYLSSITAAVFEKLGVGWNAQDTP 690
            |.:.|..|:....:...|   :.:.:||.        || |...:....|.:.||.|..:.|..|
E. coli   524 VYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWDAAQSLLATYIKLNVARHQQGQP 588

  Fly   691 LDV------ANRNKLIKWLCRYQASNCRPKVNVQFVTGHEVPS----------------PDYRET 733
            |.:      |.|..|:.       ....|.:..:.:|   :||                .:.||.
E. coli   589 LSLPVHVADAFRAVLLD-------EKIDPALAAEILT---LPSVNEMAELFDIIDPIAIAEVREA 643

  Fly   734 F-----------YCAASGADYNSYTMLWGQYYLENRTSEKNMLWAAISCTRDY---ETHYHKMII 784
            .           ..|...|:|.|      :|.:|:....|..|..|  |.|..   |||...:::
E. coli   644 LTRTLATELADELLAIYNANYQS------EYRVEHEDIAKRTLRNA--CLRFLAFGETHLADVLV 700

  Fly   785 SG--------TESVEQKKIGIARMYEENPDLVQAIFEMITEN--IMELAYNFQSWSDTAEVINDM 839
            |.        |:::......:|........|:|...:...:|  :|:..:..|:.|..|.|:.
E. coli   701 SKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWHQNGLVMDKWFILQATSPAANVLE-- 763

  Fly   840 AEYFTTREQQQLLKEFYYSNHQFFGESEELLSKSLVTVEKNLNWAETHLEG------LVKYLADR 898
                |.|...|         |:.|..|.....:||:......|.|..|.|.      ||:.|.|.
E. coli   764 ----TVRGLLQ---------HRSFTMSNPNRIRSLIGAFAGSNPAAFHAEDGSGYLFLVEMLTDL 815

  Fly   899 NGSSCLGATSLVVVLL 914
            |..:...|:.|:..|:
E. coli   816 NSRNPQVASRLIEPLI 831

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	85/368 (23%)
		ERAP1_C	566..878	CDD:463368	69/369 (19%)
pepN	NP_415452.1	pepN	1..870	CDD:237585	182/861 (21%)