Protein Alignment CG42335 and npepps

DIOPT Version :9

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001072690.1
• Gene: npepps / 780147
• XenbaseID: XB-GENE-1008338
• Length: 875
• Species: Xenopus tropicalis
• Alignment Length: 912
• Identity: 224/912 - (24%)
• Similarity: 393/912 - (43%)
• Gaps: 83/912 - (9%)

  Fly    26 RLEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHADTLDITECWLLDAAG 90
            ||...|.|.:|.|   .|:..:....|:|::..|:.|...  ..||:::...:||..........
 Frog     9 RLPTDVRPVNYGL---CLKPDLIDFTFEGKLEATVEVQNA--TNQIVMNCADIDIITASYAPEGD 68

  Fly    91 AQVEAIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSASYVERDTNVTR 155
            .::.|...:   |:...::|.:......|.|.. .|...:.|.:...|.||:.:.|... |...|
 Frog    69 EEIHATGFN---YQNEDEKVTLSFPSTLQKGAG-MLKIDFVGELNDKMKGFYRSKYATA-TGEVR 128

  Fly   156 WLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQD-RFVD-HFKE 218
            :.|:||.:..:||...||:||||:||.|.:.::.|....:::|..|.:.|....| ..|: .|..
 Frog   129 YAAVTQFEATDARRAFPCWDEPAIKATFDVILIVPKDRVALSNMNLIDRKPYPDDENLVEVKFAR 193

  Fly   219 TPVMSTYLLAFMVANYSARGNESEFAVLTRPEFY------DNTEFSYHVGQQVVSAYGELFQSPY 277
            ||:|||||:||:|..|......|...||.|  .|      :..:|:..|..:.:..|.:.|..||
 Frog   194 TPIMSTYLVAFVVGEYDFVETRSSDGVLVR--VYTPVGKAEQGKFALEVAAKTLPFYKDYFNVPY 256

  Fly   278 AELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSHMWFGD 342
            .....|::..|.   |....||||||:.|.:..|:.:|..|.. |.:::...::.||.:|.|||:
 Frog   257 PLPKIDLIAIAD---FAAGAMENWGLVTYRETALLIDPKNSCS-SSRQWVALVVGHELAHQWFGN 317

  Fly   343 SVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFV----VRQMQLIFGTDAQNGTQPMTSP 403
            .||..||::.||||.||.:.||......:|:|.:..|||    .|..:|    ||...:.|:
 Frog   318 LVTMEWWTHLWLNEGFASWIEYLCVDHCFPEYDIWTQFVSADYTRAQEL----DALENSHPI--- 375

  Fly   404 ESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLFE 468
            |..:..||::...|..|:|:|||.::||..:.:|.|:|...:..||.::...|....:|:..|.:
 Frog   376 EVSVGHPSEVDEIFDAISYSKGASVIRMLHDYIGDEDFRKGMNQYLTKFQEKNAATEDLWESLEQ 440

  Fly   469 HWPKNQDVDLVDFLTDYTEQVGYPMIIVKALQ--GNKVVTVEQSRFLLNKDDGSNATLKYTVPIT 531
            ...|    .:...:..:|:|:|:|:|.|::.|  .:.|:.:.|.:|..:....|:.:.::.|||:
 Frog   441 ASGK----PIAAVMNTWTKQMGFPLICVESEQKEDSVVLKLSQKKFCASGAPNSDDSYQWMVPIS 501

  Fly   532 FTTNLERDFYNLTPYKYLHKTVNVLWLDFTSPIDWILFNLRQSNYQRVFYDDTLREGLLLAISAT 596
            ..|:  ....:.|....:.|....:.|:...|..|:..|.....:.|..|..|:.|.||..|  .
 Frog   502 ICTS--ESPASATVKILMDKPEMTVVLEGVKPHQWVKLNPGTVGFYRTQYSTTMLESLLPGI--R 562

  Fly   597 NHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLNTVAKRLTPEQ 661
            :.|..||: |..:.:|||:.|:|..::.|:|.:.:|....|..|..|..:..||..::..|:.
 Frog   563 DLSLQPVD-RLGLQNDLFSLARAGMINTAEVLKVMEAFVNEPNYTVWSDLSCNLGILSTLLSH-- 624

  Fly   662 LPDFRIYLSSITAAVFEKLG--VGWNAQ--DTPLDVANRNKLIKWLCRYQASNCRPKVNVQF--- 719
             .||...:......||..:|  :||:.:  :..||...|..::..|.:........:...:|
 Frog   625 -TDFHEEIQCFVRDVFSPIGQRLGWDPKPGEGHLDALLRGLVLGKLGKAGHQPTLEEARRRFKEH 688

  Fly   720 VTGHEVPSPDYRETFYCAA-SGADYNSYTMLWGQYYLENRTSEKNMLWAAISCTRDYETHYHKMI 783
            |.|..|.|.|.|...|... ...|.::...:...:...:...|||.:...:....:.:.....:.
 Frog   689 VDGRNVLSADLRSPVYVTVLKHGDNSTLETMMKLHKQADMQEEKNRIERVLGAIAEQDLIKKVLS 753

  Fly   784 ISGTESVEQK-------------KIGIARMYEENPDLVQAIFEMITENIMELAYNFQSWSDTAEV 835
            .|.:|.|..:             |:|           .:..:..:.:|..||...:|.....:.:
 Frog   754 FSLSEDVRPQDTVCVIGGVAGGSKLG-----------RKCAWNFVKDNWEELYNRYQGGFLISRL 807

  Fly   836 INDMAEYFTTREQQQLLKEFYYSNHQFFGESEELLSKSLVTVEKNLNWAETHLEGLVKYLADRNG 900
            |....:.|.:.:....:|.|:.::..  ..:|..:.:....:..|..|.:...|.:..||..|..
 Frog   808 IKLSLDGFASDKMAAEIKAFFDAHPA--PSAERTVQQCCENILLNAGWLKRDAEAIHHYLLQRKP 870

  Fly   901 SS 902
            ||
 Frog   871 SS 872

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	Peptidase_M1	26..425	CDD:279741	119/410 (29%)
		M1_APN_2	34..492	CDD:189008	132/469 (28%)
		ERAP1_C	567..874	CDD:288671	63/327 (19%)
npepps	NP_001072690.1	Peptidase_M1	9..397	CDD:279741	119/410 (29%)
		M1_APN_2	17..460	CDD:189008	132/469 (28%)
		ERAP1_C	535..846	CDD:288671	63/329 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D110058at2759
OrthoFinder	1	1.000	-	-		FOG0000044
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X67
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010