Protein Alignment CG42335 and Aopep

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001276853.1
• Gene: Aopep / 72061
• MGIID: 1919311
• Length: 823
• Species: Mus musculus
• Alignment Length: 558
• Identity: 113/558 - (20%)
• Similarity: 194/558 - (34%)
• Gaps: 167/558 - (29%)

  Fly    76 DTLDITECWLLDAAGAQVEAIDIS-------------------RLIYEAATQQVRVP-------- 113
            |.|.:.:|  .|.:..:||.:|::                   :|..|.....|.:|
Mouse   141 DFLLVLDC--CDLSVLKVEEVDVAAVPGLEKFTKAPKLLATPEKLRCEIVRDLVALPADAWREQL 203

  Fly   114 --LTEAAQ-PG--------KNYTLGFKYTGHIRTDMAGFFSASYV-------------ERDTNVT 154
              .|..:| ||        .|::|..:.||  .:..|.|..|..:             ..|.| .
Mouse   204 DCYTRCSQAPGCGELLIDSDNWSLRIRKTG--TSTPADFPRAIRIWYKTKPEGQSVAWTTDQN-G 265

  Fly   155 RWLALTQMQRINARLVLPCFDEPALKAQFQLQ-------IVRPNGYQSIANTKLKETKALSQDRF 212
            |....|....||.|.:.||.:.|...:.:|..       :|..:|..|...|.|:|       .:
Mouse   266 RPCVYTMGSPINNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGENSAKPTPLRE-------GY 323

  Fly   213 VD-HFKETPVM--STYLLAF---------------MVANYSARGNESEFAVLTRPEFYDNT---- 255
            :. |:..|..|  ||:.:|.               ::..:|...:.||..:.     ||||
Mouse   324 MSWHYYVTMPMPASTFAIAVGCWTEMKPKASPPDDLMTEHSLPLSPSEADLR-----YDNTCNHM 383

  Fly   256 ------EFSYHVGQQVV---------------------------SAYGELFQSPYAELGNDVLQY 287
                  :.:....|.::                           :|:..|...|::.|  |:|..
Mouse   384 EYPCRFQSASAASQDIIPYRVFAPVCLEGACQEALLWLIPSCLSAAHSVLGTHPFSRL--DILIV 446

  Fly   288 ASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYF 352
            .::  ||..||.:..:|..|...|   .|.|.....:      :.||.:|.|||.::....|:..
Mouse   447 PTN--FPSLGMASPHIIFLSQSTL---TGTSHLCGTR------LCHEIAHSWFGLAIGARDWTEE 500

  Fly   353 WLNEAFARYYE---YFMAHQLYPDYHLDEQFV---VR----QMQLIFGTDAQNGTQPMTSPESEI 407
            ||:|.||.:.|   :..|.||.|...|::|.:   :|    |.:|....:.....:|.......:
Mouse   501 WLSEGFATHLEDIFWAEAQQLPPHEALEQQELRACLRWHRLQDELRNSPEGMQVLRPNKEETGHV 565

  Fly   408 QTPSQIAYK--------FSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFY 464
            ........|        |..:.|.||..::|.....:|.:.:...:|.::..:|....:..:...
Mouse   566 SASGASVVKHGLNPEKGFMQVHYLKGYFLLRFLTRTLGEKIYFPFLRKFVHLFHGQLILSQDFLQ 630

  Fly   465 HLFEHWPKNQDVDL--VDFLTDYTEQVGYPMIIVKALQ 500
            .|.|:.|:|:.:.|  .:.:.|:.|..|.|    ||||
Mouse   631 MLLENIPENKRLGLSVENIVRDWLECSGIP----KALQ 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	106/543 (20%)
		ERAP1_C	566..878	CDD:463368
Aopep	NP_001276853.1	GluZincin	<244..641	CDD:472708	82/422 (19%)
		Nucleolar localization signal. /evidence=ECO:0000269|PubMed:17803194	693..703
		Leuk-A4-hydro_C	710..822	CDD:462686