Protein Alignment CG42335 and Rnpepl1

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001258106.1
• Gene: Rnpepl1 / 684035
• RGDID: 1595210
• Length: 724
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 128/561 - (22%)
• Similarity: 202/561 - (36%)
• Gaps: 136/561 - (24%)

  Fly   146 YVERDTNVTRWL------------ALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIAN 198
            |...|.....||            ..||...:..|...||||.||:|..:...:..|:|.|.:.:
  Rat   164 YTSTDAPAIWWLDPELTYGNAKPFVFTQGHSVCNRSFFPCFDTPAVKCTYSAVVKAPSGVQVLMS 228

  Fly   199 TKLKETKALSQDRFVD-----HFKETPVMSTYLLAFMVANYSARGNESEFAVLTRPEFYD--NTE 256
            .        :|..:|:     ||.....:..||:|.:..:...........|...|....  .::
  Rat   229 A--------TQSAYVEEEGLYHFHMEHPVPAYLVALVAGDLKPADIGPRSRVWAEPCLLPTATSK 285

  Fly   257 FSYHVGQQVVSAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDW 321
            .|..|.|.:.:|  |....||.....|::  ...|.||...|||..|......:|
  Rat   286 LSGAVEQWLSAA--ERLYGPYMWGRYDIV--FLPPSFPIVAMENPCLTFIISSIL---------- 336

  Fly   322 SDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLY--------PDYHLDE 378
            ...||.:..:.||.:|.|||::||.:.|...||:|..|.|.:..:..:.|        ..:.||.
  Rat   337 ESDEFLVIDVIHEVAHSWFGNAVTNATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDA 401

  Fly   379 QFVVRQMQLIFGTDAQNGTQPMTSPESEIQ-------TPSQIAYKFSGIAYAKGACIVRMWRNLM 436
              :.|||:|: |.|         ||.|::|       .||.:...|:   |.||.|.|.....|.
  Rat   402 --LHRQMRLL-GED---------SPVSKLQVKLEPGVNPSHLMNLFT---YEKGYCFVYYLSQLC 451

  Fly   437 G-AENFDTAIRSYLQQYHLTNTVPYNLFYHLFEHWP--KNQDVDL---VDFLTDYTEQVGYPMII 495
            | .:.||..:|:|:::|..|:.|..:|.......:|  |.|.||.   ::| ..:....|.|:..
  Rat   452 GDPQRFDDFLRAYVEKYKFTSVVAQDLLDSFLSFFPELKEQSVDCRAGLEF-ERWLNATGPPLAE 515

  Fly   496 VKALQGNKVVTVEQSRFL------LNKDDGSNATLKYTVPITFTTNLERDFYNLTPYKYLHKTVN 554
            ....||:.:....::.|.      |.:...|.:.:..:...||.|
  Rat   516 PDLSQGSSLTRPVEALFQLWTAEPLEQAAASASAIDISKWRTFQT-------------------- 560

  Fly   555 VLWLDFTSPIDWILFNLRQSNYQRVFYDDTLREGLLLAISATNHSGIPVENR------AQIIDDL 613
            .|:||                  |:.....|.:.:::::|....|.:...|.      .||:
  Rat   561 ALFLD------------------RLLDGSPLPQEVVMSLSKCYSSLLDSMNTEIRIRWLQIV--- 604

  Fly   614 FNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLNTVA 654
              .....|.|...|.||||.....:..:|   :||:|.|.|
  Rat   605 --VRNDYYPDLHRVRRFLENQMSRMYTIP---LYEDLCTGA 640

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	95/380 (25%)
		ERAP1_C	566..878	CDD:463368	20/95 (21%)
Rnpepl1	NP_001258106.1	M1_LTA4H	30..507	CDD:341062	95/380 (25%)
		Leuk-A4-hydro_C	555..668	CDD:462686	26/132 (20%)