Protein Alignment CG42335 and Enpep

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_071587.2
• Gene: Enpep / 64017
• RGDID: 621228
• Length: 945
• Species: Rattus norvegicus
• Alignment Length: 927
• Identity: 238/927 - (25%)
• Similarity: 407/927 - (43%)
• Gaps: 124/927 - (13%)

  Fly    24 DYRLEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHADTLDITEC-WLLD 87
            ::||...:.|.||:|.:.||   :|...:.|.|||::.:  :.:.:.:.||.....||:. .|..
  Rat    82 NFRLPDFIQPVHYDLEVKVL---MEEDRYTGIVSISVNL--SKDTRDLWLHIRETRITKLPELRR 141

  Fly    88 AAGAQVEAIDISRLIYEAATQQVRVPLTE---AAQPGKN-YTLGFKYTGHIRTDMAGFFSASYVE 148
            .:|.||..    |..:|...|:..|...|   ||..|.: |.|..::.|.:...:.||:..:|.|
  Rat   142 PSGEQVPI----RRCFEYKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLNGSLVGFYRTTYTE 202

  Fly   149 RDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQDRFV 213
              ...|:.:|.|..:..:||...||||||..||.:.:.::.|..|.:::|..:::.:.|..|...
  Rat   203 --DGQTKSIAATDHEPTDARKSFPCFDEPNKKATYNISLIHPKEYSALSNMPVEKEETLDNDWKK 265

  Fly   214 DHFKETPVMSTYLLAFMVANYSARGNESE----FAVLTRPEFYDNTEFSYHVGQQVVSAYGELFQ 274
            ..|.::..|||||:.|.|..:::....|.    ..|..:|......|::.::.:.|...:.:.|.
  Rat   266 TTFMKSVPMSTYLVCFAVHQFTSIQRTSRSGKPLTVYVQPNQKQTAEYAANITKAVFDFFEDYFA 330

  Fly   275 SPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSHMW 339
            ..|:   ...|...:.|.|....||||||:.|.:..|:.:|..|.. |:::....::|||..|.|
  Rat   331 MEYS---LPKLDKIAIPDFGTGAMENWGLVTYRETNLLYDPLLSAS-SNQQRVASVVAHELVHQW 391

  Fly   340 FGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQNGTQPMTSPE 404
            ||:.||..||...||||.||.::|:...:....|:.:..|.::..:..:...|:...:.|:.
  Rat   392 FGNIVTMDWWDDLWLNEGFASFFEFLGVNHAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVV--- 453

  Fly   405 SEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLFEH 469
            ..:.||::|...|.||:|:|||.|:||.::.:..|.|....:.||:.:...|....: |:...|.
  Rat   454 VTVSTPAEITSVFDGISYSKGASILRMLQDWITPEKFQKGCQIYLENFKFKNAKTSD-FWDSLEK 517

  Fly   470 WPKNQDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLN-KDDGSN--ATLKYT--VP 529
             ..||.|.  :.:..:|.|:|||::.|...|     .|.|.||||: |.|.|.  :.|.||  :|
  Rat   518 -ASNQPVK--EVMDTWTSQMGYPVVTVSGKQ-----NVTQKRFLLDYKADPSQPPSALGYTWNIP 574

  Fly   530 ITFTTNLERDFYNLTPYKYLHK---TVNVLWLDFTSPIDWILFNLRQSNYQRVFYD----DTLRE 587
            |.:|.|...   |:|.|...::   |:|.    ..|...::..|.....:.||.|:    |.:.|
  Rat   575 IKWTENGNS---NITVYYRSNREGITLNA----NLSGDGFLKINPDHIGFYRVNYEAETWDWIAE 632

  Fly   588 GLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLNT 652
            .|     ::||......:|:..|||.|..|:||.:||........||..|.:::||..|...::.
  Rat   633 TL-----SSNHMNFSSADRSSFIDDAFALARAQLLDYEKALNLTRYLTSEKDFLPWERVISAVSY 692

  Fly   653 VAKRLTP--EQLPDFRIYLSSITAAVFEKLGVGWNAQDTPLDVAN--RNKLIKWLCRYQASNCRP 713
            :......  |..|....|..|....:.:.|  ||  |||...:..  |..::.:.|:..|.....
  Rat   693 IISMFEDDRELYPLIETYFRSQVKPIADSL--GW--QDTGSHITKLLRASVLGFACKMGAGEALG 753

  Fly   714 KVNVQF---VTGHE-VPSP----DYRETFYCAASGADYNSYTMLWGQYYLENRTSEKNMLWAAIS 770
            ..:..|   :.|:| :|..    .||.....:.:.|.:| ||:  .||...:...||..|...::
  Rat   754 NASQLFEAWLKGNESIPVNLRLLVYRYGMQNSGNEAAWN-YTL--EQYQKTSLAQEKEKLLYGLA 815

  Fly   771 CTRDYETHYHKMIISGTESVEQKKIGIARMYE--ENPDLV--QAIFEMI-----TENIMELAYNF 826
            ..:|...                   :||..|  ::|:::  |.:|.:|     ......:|:|:
  Rat   816 SVKDVTL-------------------LARYLEMLKDPNIIKTQDVFTVIRYISYNSYGKSMAWNW 861

  Fly   827 --QSWSDTAE--VIND--------MAEYFTTREQQQLLKEFY--YSNHQFFGESEELLSKSLVTV 877
              .:|.....  .|||        :||.|.|..|...::.|:  |.|   .|...:...:.|.||
  Rat   862 IQLNWDYLVNRFTINDRYLGRIVTIAEPFNTELQLWQMQSFFAKYPN---AGAGAKPREQVLETV 923

  Fly   878 EKNLNWAETHLEGLVKY 894
            :.|:.|.:.:.:.:.::
  Rat   924 KNNIEWLKLNRKSISEW 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	125/461 (27%)
		ERAP1_C	566..878	CDD:463368	78/350 (22%)
Enpep	NP_071587.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..77
		M1_APN-Q_like	92..531	CDD:341064	125/460 (27%)
		ERAP1_C	607..925	CDD:463368	79/351 (23%)