Protein Alignment CG42335 and SP1029

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Alignment Length: 938
• Identity: 256/938 - (27%)
• Similarity: 428/938 - (45%)
• Gaps: 128/938 - (13%)

  Fly    25 YRLEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLE-VQQIILHADTLDITECWL-LD 87
            |||..|:.|..|:|.|..|..:.|...|.|.|.|   ::..|| .:.:.||:..|.|.|..: |.
  Fly    32 YRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKI---LIEALENTKNVTLHSKNLTIDESQITLR 93

  Fly    88 AAGAQVE--------AIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSA 144
            ..|.:.:        |::.|...|...|.|..:       .|..|.|...:...:...:.|::.:
  Fly    94 QIGGEGKKENCVSSTAVNPSHDFYILNTCQELL-------AGNTYELYMPFAADLNRQLEGYYRS 151

  Fly   145 SYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQ 209
            ||.:...|:|:|:::||.:..:|||..||||||..||.|.:.:.....|.:|:|...||||  ..
  Fly   152 SYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKKYTAISNMPEKETK--PH 214

  Fly   210 DRFVDH----FKETPVMSTYLLAFMVANYSAR----GNESEFAVLTRPEFYDNTEFSYHVGQQVV 266
            :...|:    |:|:..|||||:|:.|.::|.:    .|.:.|....||...|..:::...|.:|:
  Fly   215 ETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFRTWARPNAIDQCDYAAQFGPKVL 279

  Fly   267 SAYGELF--QSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIR 329
            ..|.:.|  :.|..:     :...:.|.|....||||||:.|.:..|:....:| ..:||:....
  Fly   280 QYYEQFFGIKFPLPK-----IDQIAVPDFSAGAMENWGLVTYREIALLYSAAHS-SLADKQRVAS 338

  Fly   330 IIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQ 394
            ::|||.:|.|||:.||..||:..||||.||.|........:.|::...||..:..:..||..||.
  Fly   339 VVAHELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQESLSNLLTIFRRDAL 403

  Fly   395 NGTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVP 459
            ..:.|::.|   ||..|:|:..|..|:|.||:.::||....:|.|:|.:.:::|||::...|...
  Fly   404 ESSHPISRP---IQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQAYLQKFSYKNAEQ 465

  Fly   460 YNLF------YHLFEHWPKNQDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLNKDD 518
            .||:      .|.:...||:.|:..:  :..:|.|.|||:|.|......:...:.|.|:|||
  Fly   466 DNLWESLTQAAHKYRSLPKSYDIKSI--MDSWTLQTGYPVINVTRDYAARTAKLNQERYLLN--- 525

  Fly   519 GSNATLKYT-----VPITFTTNLERDFYNLTPYKY---------LHKTVNVLWLDFTSPIDWILF 569
             :.....|.     ||:::||...:||.|..|..:         |.||:.    |...|..|::|
  Fly   526 -TQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPKTIQ----DLPGPDQWVIF 585

  Fly   570 NLRQSNYQRVFYDDTLREGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYL 634
            |.:.|...:|.||....:.|:..::..:...|.|.||||:|||....|.....||....|.:|||
  Fly   586 NTQLSTLYKVNYDAQNWKLLIETLTNGDFERIHVINRAQLIDDALYLAWTGEQDYEIAMRLIEYL 650

  Fly   635 AKEVEYVPWYAVYENLNTVAKRLTPEQLPDFRI---YLSSITAAVFEKLGVGWN-------AQDT 689
            .:|.||:||.:.:|||..|.:.:  .|.|||..   |:..:...::|.|. |.|       .||
  Fly   651 QREREYLPWKSAFENLKRVGRIV--RQTPDFEFFKRYMKKLILPIYEHLN-GINDTFSAIPQQD- 711

  Fly   690 PLDVANRNKLIKWLCRYQASNCRPKVNVQFVTGHEVPSPD--------YRETFYCAA--SGADYN 744
              .|..:..::.|.|:||..:|.|:....:.......:||        .|.|.||.:  .|:| :
  Fly   712 --QVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDEKNPVPINVRSTVYCTSIKHGSD-S 773

  Fly   745 SYTMLWGQYYLENRTSEKNMLWAAISCTRD--YETHYHKMIISGTESVEQK------------KI 795
            .:..||.:|...|..:||..:..|:.|:|:  ....|.::.....|::.::            ::
  Fly   774 DWEFLWTRYKKSNVAAEKRTILTALGCSREVWLLQRYLELTFDPKEAIRKQDSMWAFQAVAFNEV 838

  Fly   796 G--IARMY-EENPDLVQAIFEMITENIMELAYNFQSWSDTAEVINDMAEYFTTREQQQLLKEFYY 857
            |  :|:.| .:|.|.:...:..:|:             |.:.:::.::|...|.......|:|..
  Fly   839 GFLLAKKYFMDNVDFIYKFYHPLTK-------------DMSRLLSPLSEQVITLSDFNEFKDFVN 890

  Fly   858 SNHQFFGESEELLSKSLVTVEKNLNWAE 885
            ::.|.....|:.:.::|..:..|:.|.|
  Fly   891 NSRQSLKGLEQAIQQTLEIMLTNVQWKE 918

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	138/478 (29%)
		ERAP1_C	566..878	CDD:463368	84/348 (24%)
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	138/477 (29%)
		ERAP1_C	582..910	CDD:463368	84/347 (24%)