Protein Alignment CG42335 and CG4467

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001036747.1
• Gene: CG4467 / 42747
• FlyBaseID: FBgn0039064
• Length: 1125
• Species: Drosophila melanogaster
• Alignment Length: 1071
• Identity: 235/1071 - (21%)
• Similarity: 381/1071 - (35%)
• Gaps: 293/1071 - (27%)

  Fly    27 LEGSVVPSHYNLTIGVLRNSVEP--TIFD--GEVSITLRVVGTLEVQQIILHADTLDITECWLLD 87
            |..||.|..|.:||       .|  |..|  |:|:|.|.|  ..|...|:||...|::||..::
  Fly   138 LPTSVRPLRYMVTI-------HPNLTTLDVKGQVTIDLHV--EKETNFIVLHIQDLNVTEKAIV- 192

  Fly    88 AAGAQVEAIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSASYVERDTN 152
            ..|.:..|:.|.:::.....||:.:.:.|..:...||||..::...:..:..||:...| |....
  Fly   193 TPGPKGYALKIVKVLEFPPRQQLYIEVKERLKKKSNYTLNLRWYSKLNPEPEGFYVDQY-ESSNG 256

  Fly   153 VTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETK--------ALSQ 209
            |.|.||.|..:...||...||||||.::|.|::.:.|...:..::|:.:..|:        .|.:
  Fly   257 VERLLAATVFRPNGARRAFPCFDEPHVRAPFRISVFRDRFHIGLSNSIVHTTEDVGFYMGTGLLR 321

  Fly   210 DRFVDHFKETPVMSTYLLAFMVANY---------------------------SARGNE------- 240
            |.|:    |||.:....:|::|:::                           ||:.|.
  Fly   322 DDFI----ETPPLPADAVAWVVSDFQRESLQPSAAYIPTTPAPPGSGVGGKKSAQLNNYTQLKGK 382

  Fly   241 ----SEFAVLT--------------------------------RPEFYDNTEFSYHVGQQVVSAY 269
                .....||                                :|.  :.|..|...|..:..|.
  Fly   383 NPPVRNITALTHSLNVNLTPRQNLTVVQPTTTTAWPVNLNGNGKPS--NLTSLSQSTGSSIKRAP 445

  Fly   270 GELFQSP---------YAELGNDVLQYASS----------------PRFPHNGMENWGLIIYSDD 309
            ...|.:|         ......|||:|..:                |....|.:.:.||:.....
  Fly   446 SYTFYAPRDLLIRSSFILHTSRDVLEYLQTWLDISYPLTKVDFVALPSLDRNMISSLGLVTLKTS 510

  Fly   310 VLIQEPGYSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDY 374
            .|......:.:  ..:|:...||......:||...:.......||.|..   .:|...|.|.|
  Fly   511 FLTDPSSITSE--QYQFSALRIAEAMVRQFFGGITSRKVLKDVWLWEGL---IQYLGIHALAP-- 568

  Fly   375 HLDEQFVVRQMQL------------IFGTDA-QNGT-QPMTSPESEIQTPSQIAYKFSGIAYAKG 425
             |.|.:.:|:|.|            |.|.|: .||| ....:.|..:|               |.
  Fly   569 -LQETWPLREMYLLKMATAALDIDAIQGWDSIMNGTSHDGNNEEFFVQ---------------KT 617

  Fly   426 ACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLFEHW-----PKNQDVDLVDFLTDY 485
            |.|..|....:|.:.|...:.|:|:........|.:|       |     ..|...::.|.:|.:
  Fly   618 AAIFSMLHTAIGEDRFRGCLGSFLKVNRFRTAEPTDL-------WTICTKKANGSKNIKDMMTLW 675

  Fly   486 TEQVGYPMIIVKALQGNKVVTVEQ-----SRFLLNKD---DGSN---ATLKYT-VPITFTTNLER 538
            |.|.|:|::.|..: ||. :::.|     :.||...|   ||:|   .||..| :|.|..|..:.
  Fly   676 THQPGFPLLTVTKM-GNS-ISISQRPFRPAEFLAIHDDSYDGNNYNKTTLNATDMPSTVATTTQG 738

  Fly   539 DFYNLTPY-------KYLHKTVNV---LWLD-----FTSP--IDWILFNLRQSNYQRVFYDDTLR 586
            ..:.:.|:       .|:....||   ||:.     |..|  :.||..|..|:.|.||.|:|...
  Fly   739 SKHKVAPHMKWIFPVTYVTDINNVSETLWMQNVDVTFNVPENVKWIKVNAIQNGYYRVVYNDDNW 803

  Fly   587 EGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLN 651
            ..|:..::| |.:....|:|..::.|.|....|..:........::||..|..|.|......:|.
  Fly   804 ASLIEELAA-NPNRFTSEDRLGMLSDAFTLCHANLLPCEITMNMIQYLPSETHYGPMALALRHLE 867

  Fly   652 TVAKRLTPEQ----LPDFRIYLSSITAAVFEKLGVGWNAQDTPLDVANRNKLIKWLCRYQASNCR 712
            ...:.|...:    |.:|   :....:.|.||  |||:...   |||.|  |:           |
  Fly   868 KWRRILKYSECFLMLSEF---IKMKISTVMEK--VGWSDDG---DVATR--LL-----------R 911

  Fly   713 PKVNVQFVTGHEVPS--------------------PDYRETFYCAA--SGADYNSYTMLWGQYYL 755
            |:|.:..|...::.|                    |:.||..|..:  || :|..:...|.::..
  Fly   912 PEVLLASVLWEDIDSITKAKNMLNQYLYYNGTAIPPNLREVVYTGSILSG-EYIYWQHCWERFVN 975

  Fly   756 ENRTS----EKNMLWAAISCTRDYETHYHKMIIS-----GTESVEQKKIGIARMYEENPDLVQAI 811
            ..|||    |:..|..|:..|:|  ......::|     .||.|.|              :::||
  Fly   976 LQRTSETFVERMQLLRALGRTKD--AWLQNRLLSHVTMLPTEEVVQ--------------VLKAI 1024

  Fly   812 FEMITENIMELAYNFQSWSDT-----------AEVINDMAEYFTTREQQQLLKEFYYSNHQF-FG 864
            ....|...|...:....|.:.           |:||:.:.:|..|:.....||...   |:| .|
  Fly  1025 AGTPTGGAMACRFLQAKWFELEKRLGPGTISFAKVISAITQYGATKFDYDELKSLV---HRFGRG 1086

  Fly   865 ESEELLSKSLVTVEKNLNWAETHLEGLVKYL 895
            ....:|:.:|.:|..|:.|.......|.|::
  Fly  1087 HGMSVLNMTLSSVASNVEWVARSQTSLYKWV 1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	118/578 (20%)
		ERAP1_C	566..878	CDD:463368	80/358 (22%)
CG4467	NP_001036747.1	GluZincin	145..677	CDD:472708	118/578 (20%)
		ERAP1_C	783..1078	CDD:463368	74/333 (22%)