DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42335 and Aopep

DIOPT Version :9

Sequence 1:	NP_732655.3	Gene:	CG42335 / 42558	FlyBaseID:	FBgn0259237	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	XP_008769651.1	Gene:	Aopep / 290963	RGDID:	1309592	Length:	886	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	94/414 - (22%)
Similarity:	157/414 - (37%)	Gaps:	104/414 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly   165 INARLVLPCFDEPALKAQFQLQ-------IVRPNGYQSIANTKLKETKALSQDRFVD-HFKETPV 221
            ||.|.:.||.:.|...:.:|..       :|..:|.:|...|.|:|       .::. |:..|..
  Rat   340 INNRALFPCQEPPVAMSTWQATVRAAASFVVLMSGEKSAKPTPLRE-------GYMSWHYYVTMP 397

  Fly   222 M--STYLLAF-----MVANYSARGNESEFAVLTRP---EF-YDNT----EF-------------- 257
            |  ||:.:|.     |....|...:.:|..:..||   :| |.||    |:
  Rat   398 MPASTFTIAVGCWTEMKPKTSPLDDLTEHTLPLRPSDADFRYGNTCSHMEYPCRFQSASAATQNI 462

  Fly   258 -SYHVGQQVV------------------SAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGL 303
             .|.|...|.                  :|:..|...|::.|  |:|...::  ||..||.:..:
  Rat   463 IPYRVFAPVCLEGACREALLWLIPSCLSAAHSVLGTHPFSRL--DILIVPTN--FPSLGMASPHI 523

  Fly   304 IIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYE---YF 365
            |..|...|   .|.|.....:      :.||.:|.|||.::....|:..||:|.||.:.|   :.
  Rat   524 IFLSQSTL---TGTSHLCGTR------LCHEIAHAWFGLAIGARDWTEEWLSEGFATHLEDIFWA 579

  Fly   366 MAHQLYPDYHLDEQFV---VRQMQLIFGTDAQNGTQPM--------------TSPESEIQTPSQI 413
            .|.||.|...|::|.:   :|..:|  ..:.||..:.|              .|..|.::.....
  Rat   580 EAQQLPPHEALEQQELRACLRWHRL--QDELQNSPEGMQVLRPNKEKTGHVSASGASVVKNGLNP 642

  Fly   414 AYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPYNLFYHLFEHWPKNQ--DV 476
            ...|..:.|.||..::|.....:|.|.:...:|.::..:|....:..:....|.|..|:|:  .:
  Rat   643 EKGFMQVHYLKGYFLLRFLARTLGEETYFPFLRKFVHLFHGQLILSQDFLQMLLESIPENKRFGL 707

  Fly   477 DLVDFLTDYTEQVGYPMIIVKALQ 500
            .:.:.:.|:.|..|.|    ||||
  Rat   708 SVENIVGDWLECPGIP----KALQ 727

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	Peptidase_M1	26..425	CDD:279741	75/335 (22%)
		M1_APN_2	34..492	CDD:189008	89/404 (22%)
		ERAP1_C	567..874	CDD:288671
Aopep	XP_008769651.1	GluZincin	250..697	CDD:301352	83/378 (22%)
Aopep	XP_008769651.1	Leuk-A4-hydro_C	743..884	CDD:286244
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910