Protein Alignment CG42335 and AC3.5

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001256214.1
• Gene: AC3.5 / 179447
• WormBaseID: WBGene00007071
• Length: 1090
• Species: Caenorhabditis elegans
• Alignment Length: 978
• Identity: 201/978 - (20%)
• Similarity: 377/978 - (38%)
• Gaps: 188/978 - (19%)

  Fly    43 LRNSVEPTIFDGEVSITLRVVGT---------LEVQQ----IILHADTLDIT------------- 81
            |..:|:|..:|  ||::.:|.|.         |.:::    |:|:|..::.|
 Worm   156 LPKNVQPVWYD--VSLSPKVGGNGTMGLAHVKLNIEEPTNKIVLNAKDIEFTRNLEKIQLSKEVT 218

  Fly    82 -----------------------ECWLLDAAGAQVEA-----------IDISRLIYEAATQQVRV 112
                                   |.....|.....|:           |.::.:.::...::|.:
 Worm   219 KRAKKSVDSGTNSTSEMPEGSGEEAMATTATTTTTESTTPVSSFVDTGIKVTNIEFDENLEKVTL 283

  Fly   113 PLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSASYVERDTNVTRWLALTQMQRINARLVLPCFDEP 177
            .|.:..:.|....|...:|..: ::..|.....| :......:.:..||......|.|.|.||:.
 Worm   284 TLDQELKKGSTVVLKIPFTSKV-SNNNGLKEYKY-KNSEGKEQSMFTTQPSYSYLRHVFPSFDQE 346

  Fly   178 ALKAQFQLQIVRPNGYQSIANTKLK-----ETKALSQDRFVDHFKETPVMSTYLLAFMVANYSAR 237
            |.||...:.::...|...:|||.:|     :.:..:.::.:|        ..:::..:||:....
 Worm   347 AFKAPAAITLMHSKGSIVVANTGVKTKDDGDAQTSTLNKVLD--------PDFVIGDLVASEVNT 403

  Fly   238 GNESEFAVLTRPEFYDNTEFSYHVGQQVVSAYGELFQS------------PYAELGNDVLQYASS 290
            .:.....:.||||...:||.|.....|.:.|...:.||            |..:.||.|     |
 Worm   404 TSGITIRIWTRPEVKHSTEQSLDYANQAIDAMEHILQSRLESKSLDIVAVPGFQTGNRV-----S 463

  Fly   291 PRFPHNGMENWGLIIYSDDVLIQEPGYSDDWSDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLN 355
            |.|         :::..:|:|..|  .|:|.:.|....|:|::..:..|||.......:..||||
 Worm   464 PSF---------IVLPEEDILYNE--QSNDINQKTRIARMISNRIAAQWFGGITNPEEFGTFWLN 517

  Fly   356 EAFARYYEYFMAHQLYPDYHLDEQFVVRQMQLIFGTDAQNGTQPM----TSPESEIQTPSQIAYK 416
            ||..|:.|.....::. |.:.|:.:.. :|:.|...||...:||:    ....::|   ::|.::
 Worm   518 EALPRFLEVEALEKIL-DINSDDLWTY-EMEKILERDATATSQPLRVKNVFSSADI---AEIDHE 577

  Fly   417 FSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQYHLTNTVPY-NLFYHLFEH--------WPK 472
            |.|   .|||.::||.:..:|...|:.||||::..|.  :..|| :..:..||.        | .
 Worm   578 FIG---KKGAAVLRMIQKSVGVNVFNKAIRSFVSSYR--SAYPYDDGLWKSFEKALGGKLKGW-N 636

  Fly   473 NQDVDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLNKDDGSNATLKYTVPITFTTNLE 537
            |:.:|:..|:..:.:|:|:|::.|:.|. ::.|.:.|.||   |:|       :.....|.....
 Worm   637 NEPLDVAKFVNTWVDQIGFPLVSVEKLD-DETVELSQERF---KND-------HKTKEQFKFRNA 690

  Fly   538 RDFYNLTPYKYLHKT---VNVLWLD--FTSPI---DWILFNLRQSNYQRVFYDDTLREGLLLAIS 594
            :.::|.....:|..:   .||.||.  |..|:   |.|..|...:...||.|::.....:...:.
 Worm   691 KYWFNWEVPLFLKSSGPVGNVSWLHEAFRLPLNTSDSIYLNTDSNGVYRVNYEEKRWNDIAKQLE 755

  Fly   595 ATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVFRFLEYLAKEVEYVPWYAVYENLNTVAKRLTP 659
             .:|..:....||::|.|:|..|.:..:.:........||..|...|||.........:.:||..
 Worm   756 -KSHGKLSERTRARLISDVFALANSGALPFETALNVTSYLPMETATVPWLIATRIFKKLTERLEG 819

  Fly   660 EQLPDFRIYLSSITAAVFEKLGVGWNAQDTPLDVANRN--------KLIKWLCRYQASNCRPKVN 716
            ..:.|      .:.:.:::|:...:....:....|:.|        .|:..:...:......|:|
 Worm   820 APIQD------KLNSFIYQKIHKKFEEISSSPGEASSNYLKNRLYANLLDLMAIVKPEKSNEKLN 878

  Fly   717 VQFVTG---------------HEVPSPDYRETFYCAASGADYNSYTMLWGQYYLENRT---SEKN 763
            ..||.|               .|||. |.||..||  :|.::.:.|:......|..:.   :||:
 Worm   879 ELFVEGFLAPCQFSGNFSSDCSEVPG-DLREKVYC--NGVEFGNDTVFETVRELAEKEVDGAEKD 940

  Fly   764 MLWAAISCTRDYETHYHKMIISGTESVEQKKIGIARMYEENPDLVQAIFEMITEN-IMELAYNFQ 827
            :|..:::|.||... ..::|:....|.....: :.|.....|...:.....|.:| ...|...|:
 Worm   941 LLQNSLACFRDPRA-LRRLILDNLNSTSTVTL-LLRKMNSRPVGKEIATNWIIDNWSTVLKKKFK 1003

  Fly   828 SWSDTAEVINDMAEYFTTREQQQLLKEFYYSNHQFFGESEELLSKSLVTVEKNLNWAETHLEGLV 892
            :..:|...|.| |......|:::.:.|.:..:|.......|.|.|.:.....::.|.:..:..|.
 Worm  1004 NDPETLNAIAD-AGIILDNEREKSMIETFMEHHHKSTHGIESLDKKIEEATTDIYWRKQKINELN 1067

  Fly   893 KYL 895
            .||
 Worm  1068 DYL 1070

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	111/533 (21%)
		ERAP1_C	566..878	CDD:463368	65/338 (19%)
AC3.5	NP_001256214.1	GluZincin	165..651	CDD:472708	108/524 (21%)
		beta-trefoil_FSCN-like	<685..741	CDD:483951	13/55 (24%)
		ERAP1_C	728..1056	CDD:463368	65/340 (19%)