Protein Alignment CG42335 and ltah-1.1

DIOPT Version :9

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: NP_001023056.1
• Gene: ltah-1.1 / 178176
• WormBaseID: WBGene00016589
• Length: 609
• Species: Caenorhabditis elegans
• Alignment Length: 595
• Identity: 142/595 - (23%)
• Similarity: 230/595 - (38%)
• Gaps: 153/595 - (25%)

  Fly    20 TNAADYRLEGSVVPSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHADTLDITECW 84
            :.||:|.   .|..|||.|...|   ..|.....|:|||||.|  ..:.::|:|  ||.|::
 Worm    10 STAANYE---QVTVSHYALKWKV---DFEKKHIAGDVSITLDV--KQDTERIVL--DTRDLS--- 61

  Fly    85 LLDAAGAQVEAIDIS--------RLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGF 141
                  .|..|::::        .|....|..|..|..||:.:.|....|..||..........|
 Worm    62 ------VQSVALNLNGEPKKAGFTLEDNQALGQKLVITTESLKSGDRPVLEIKYESSNNAAALQF 120

  Fly   142 FSASYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKA 206
            .:|   |:.|:.......:|.|.||||.::||.|.|::|:.::.::..|.|...:.:       |
 Worm   121 LTA---EQTTDRVAPYLFSQCQAINARSIVPCMDTPSVKSTYEAEVCVPIGLTCLMS-------A 175

  Fly   207 LSQ--------DRFVDHFKETPVMSTYLLAFMVANYSARGNESEFAVLTRP-----EFYD--NTE 256
            :.|        .|.:..||:...:.:||||.:|.:...:......||...|     .||:  .||
 Worm   176 IGQGSTPSECGKRTIFSFKQPVSIPSYLLAIVVGHLERKEISERCAVWAEPSQAEASFYEFAETE 240

  Fly   257 FSYHVGQQVVSAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDW 321
            ....|.:.|.        .||.....|::...::  ||..||||..|...:..:|.
 Worm   241 KILKVAEDVA--------GPYVWGRYDLVVLPAT--FPFGGMENPCLTFITPTLLA--------- 286

  Fly   322 SDKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQF------ 380
            .|:.. :.:||||.||.|.|:.||...|.:|||||.|..:.|..:..::|.:  |:.||
 Worm   287 GDRSL-VNVIAHEISHSWTGNLVTNFSWEHFWLNEGFTVFLERKIHGKMYGE--LERQFESESGY 348

  Fly   381 ---VVRQMQLIFGTD------AQN-GTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNL 435
               :||.:..:||.|      .|| |.   ..|:.          .||.:.|.||:.::......
 Worm   349 EEALVRTVNDVFGPDHEYTKLVQNLGN---ADPDD----------AFSSVPYEKGSALLFTIEQA 400

  Fly   436 MGAEN-FDTAIRSYLQQYH----------------------LTNTVPYNLFYH--------LFEH 469
            :|..: |:..:|.|:|:|.                      :.:.:.:||:.|        .::.
 Worm   401 LGDNSRFEQFLRDYIQKYAYKTVSTEEWKEYLYDSFTDKKVILDNIDWNLWLHKAGLPPKPKYDS 465

  Fly   470 WPKNQDVDL-VDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSRFLLNK----------------D 517
            .|.....|| ..:.|:.:|......:..|.....|:..::..|  :||                |
 Worm   466 TPMQACKDLAAKWTTEGSEAPTDGEVFAKMSNSQKLAVLDAVR--VNKTMFGDRMPALTATYKLD 528

  Fly   518 DGSNATLKYT 527
            ...||.||::
 Worm   529 QAKNAELKFS 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	Peptidase_M1	26..425	CDD:279741	113/437 (26%)
		M1_APN_2	34..492	CDD:189008	128/528 (24%)
		ERAP1_C	567..874	CDD:288671
ltah-1.1	NP_001023056.1	M1_LTA4H	8..453	CDD:189006	126/506 (25%)
		Leuk-A4-hydro_C	468..608	CDD:312599	14/73 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910