DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42335 and mnp-1

DIOPT Version :9

Sequence 1:	NP_732655.3	Gene:	CG42335 / 42558	FlyBaseID:	FBgn0259237	Length:	924	Species:	Drosophila melanogaster
Sequence 2:	NP_497878.1	Gene:	mnp-1 / 175564	WormBaseID:	WBGene00007139	Length:	781	Species:	Caenorhabditis elegans

Alignment Length:	240	Identity:	54/240 - (22%)
Similarity:	90/240 - (37%)	Gaps:	56/240 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    33 PSHYNLTIGVLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHA---------DTLDITECWLLDA 88
            |.||.|.|.:  ..|...:.:|.:.:......  :||.|.||:         |.:.:..|    .
Worm   177 PIHYVLNITI--RDVRKPVLEGHMQLFASTKD--QVQAISLHSVKIHNLENRDRIHVVNC----N 233

  Fly    89 AGAQVEAIDISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFFSAS---YVERD 150
            .|   |.|.:||:  ......:.:.|.::...|.|          :|.|:.||.||.   :|.:.
Worm   234 TG---ETICVSRV--HQIDDLIHLELAQSISSGVN----------LRVDIDGFISADSGPHVFKQ 283

  Fly   151 TNVTRWLALTQM-----QRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKALSQD 210
            ....:| .:.||     :..:||.|.|.||....|:.|.|.:.......:|||:.:....:.|.
Worm   284 IPTAKW-RVPQMIGSVFEPTSARHVFPSFDLHNQKSTFNLCLNHGPSMSAIANSLINPNVSTSG- 346

  Fly   211 RFVDHFKETPVMSTYLLAFMVANYSARGNESEFAVLTRPEFYDNT 255
              :..|::|..:....|:|:...            .|.|.||:.|
Worm   347 --ISCFEKTVPLIAQQLSFVAFE------------KTNPLFYNTT 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	Peptidase_M1	26..425	CDD:279741	54/240 (23%)
		M1_APN_2	34..492	CDD:189008	53/239 (22%)
		ERAP1_C	567..874	CDD:288671
mnp-1	NP_497878.1	Peptidase_M1	172..556	CDD:279741	54/240 (23%)
		GluZincin	<294..>480	CDD:301352	23/99 (23%)
		GluZincin	<547..602	CDD:301352
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11533
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010