Protein Alignment CG42335 and anpep

DIOPT Version :10

• Sequence 1: NP_732655.3
• Gene: CG42335 / 42558
• FlyBaseID: FBgn0259237
• Length: 924
• Species: Drosophila melanogaster
• Sequence 2: XP_031755081.1
• Gene: anpep / 100492262
• XenbaseID: XB-GENE-981369
• Length: 977
• Species: Xenopus tropicalis
• Alignment Length: 942
• Identity: 264/942 - (28%)
• Similarity: 441/942 - (46%)
• Gaps: 120/942 - (12%)

  Fly    25 YRLEGSVVPSHYNLTIG--VLRNSVEPTIFDGEVSITLRVVGTLEVQQIILHADTLDITECWLLD 87
            |||..::.|.||::.:.  :::|:....:|.|:  .|...:.......||:|::.|:.|:....|
 Frog    83 YRLPKTLSPVHYDVELQPFLVKNADGLYVFRGK--STAFFICNDATDLIIIHSNKLNHTKFNSFD 145

  Fly    88 AA---GAQVEAI-------DISRLIYEAATQQVRVPLTEAAQPGKNYTLGFKYTGHIRTDMAGFF 142
            |.   ||...|:       |...|:.:||...|         |||.|.|..::.|.:..|:|||:
 Frog   146 AKLQDGATDVALKSTFFQKDKQFLVVQAAANLV---------PGKQYGLYTEFVGELADDLAGFY 201

  Fly   143 SASYVERDTNVTRWLALTQMQRINARLVLPCFDEPALKAQFQLQIVRPNGYQSIANTKLKETKAL 207
            .:.|:|  ..||:.:|.||||..:||...|||||||:||.|.:.:.....|::::|.:..:...:
 Frog   202 RSEYLE--DGVTKIIATTQMQAPDARKAFPCFDEPAMKATFNITLKYRQPYKAMSNMREIDRSTV 264

  Fly   208 SQDR---FVDHFKETPVMSTYLLAFMVANYSARGNESEFAVLTRPEFY---------DNTEFSYH 260
            ::|.   .|..|.:||.||:||:||:|:.:.|.|:... |.:|..:.:         :..|::..
 Frog   265 TEDGQQWTVSKFDKTPKMSSYLVAFIVSEFEAVGDPGN-ATVTGVQIWGRKKAIQDENQGEYALS 328

  Fly   261 VGQQVVSAYGELFQSPYAELGNDVLQYASSPRFPHNGMENWGLIIYSDDVLIQEPGYSDDWS--- 322
            |.:.::..:.|.:::||....:|   ..:.|.|....||||||:.|.:..|:    :.|..|
 Frog   329 VTKPILDFFAEYYRTPYPLPKSD---QVALPDFSAGAMENWGLVTYRETALL----FDDQVSSIG 386

  Fly   323 DKEFAIRIIAHETSHMWFGDSVTFSWWSYFWLNEAFARYYEYFMAHQLYPDYHLDEQFVVRQMQL 387
            :||..:.:||||.:|.|||:.||..||:..||||.||.|.||..|.:..|::::.:..|:..:..
 Frog   387 NKERVVTVIAHELAHQWFGNLVTIRWWNDLWLNEGFASYVEYLGADKAEPNWNIKDLIVLNDVHR 451

  Fly   388 IFGTDAQNGTQPMTSPESEIQTPSQIAYKFSGIAYAKGACIVRMWRNLMGAENFDTAIRSYLQQY 452
            :...||...:.|:||.|.|:.:||:|:..|..|||:|||.::||....:....|...:.|||:.:
 Frog   452 VMAVDALASSHPLTSREDEVNSPSEISALFDSIAYSKGASVIRMLSEFLTEPLFVDGLASYLKGF 516

  Fly   453 HLTNTVPYNLFYHLFEHWPKNQD------VDLVDFLTDYTEQVGYPMIIVKALQGNKVVTVEQSR 511
            ..:|||..:|:.||  .|..|..      :.:.|.:..:..|:|:|::.:....|  |||  |..
 Frog   517 EYSNTVYSDLWTHL--QWAVNNQTAVKLPLPIKDIMDTWVLQMGFPVVKIDTATG--VVT--QKH 575

  Fly   512 FLLNKDD----GSNATLKYTVPITFTTNLERDFYNLTPYKYLHKTVNVLWLDFTSPI-------- 564
            |||:.|.    .|....|:.|||:              ||...|..|: ||...|..
 Frog   576 FLLDPDSVVTRPSPFDYKWKVPIS--------------YKISSKEDNI-WLQNESETVEDFKITG 625

  Fly   565 -DWILFNLRQSNYQRVFYDDTLREGLLLAISATNHSGIPVENRAQIIDDLFNFAQAQYVDYADVF 628
             ||:|.||..:.|.||.|||.....||..:. |:|..|||.||||||||.||.|:|:.:......
 Frog   626 NDWLLVNLNVTGYYRVNYDDNNWSRLLNQLQ-TSHQAIPVINRAQIIDDAFNLARAKQITTIQAL 689

  Fly   629 RFLEYLAKEVEYVPWYAVYENLNTVAKRL-TPEQLPDFRIYLSSITAAVFE--KLGVGWNAQDTP 690
            ...:|::.:.||:||.|....|:...:.. ..|.....:.|:......:||  |...| |..:.|
 Frog   690 DTTKYISADREYMPWQAALSGLSYFTQMFDRTEVFGPMKKYMKMQVNPLFEYFKQETG-NWTNRP 753

  Fly   691 LDVANRNKLIKWL---CRYQASNCRPKVNVQFVTGHEVPS-----PDYRETFYC--AASGADYNS 745
            :.:.::...|..|   |.|...:|....:..|......|.     |:.|...||  .|.|.: ..
 Frog   754 VSLTDQYCEINTLSTACSYDIEDCLKFASELFSQWMATPQQNNIHPNLRTNVYCTAVAQGGE-QE 817

  Fly   746 YTMLWGQYYLENRTSEKNMLWAAISCTRD--YETHYHKMIISGTESVEQKKIGIARMYEENP--- 805
            :..:|.::.|.:...|::.|.||::|:::  ....:.:..:..|....|..:........||
 Frog   818 WNFVWDRFQLTDIAQEQDKLRAALACSKEPWILNRFLEYSLDPTMIRRQDAVSTISSVVNNPIGQ 882

  Fly   806 ----DLVQAIFEMITENIMELAYNFQSWSDTAEVINDMAEYFTTR-EQQQLLKEFYYSNHQFFGE 865
                |.|:|.::.:.....|.:::|      ..:|..:...|:|. |.||||:....:.:..||.
 Frog   883 SLAWDFVRAKWKTLYSMFGESSFSF------GNLIERVTRRFSTEFELQQLLQFKADNQNPGFGT 941

  Fly   866 SEELLSKSLVTVEKNLNWAETHLEGLVKYLAD 897
            :.:.|.:::...:.|:||...:...:.|:..|
 Frog   942 ASQALEQAIEKTKANINWVNQNKAAVKKWFED 973

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42335	NP_732655.3	M1_APN-Q_like	34..487	CDD:341064	146/485 (30%)
		ERAP1_C	566..878	CDD:463368	84/334 (25%)
anpep	XP_031755081.1	M1_APN-Q_like	92..555	CDD:341064	146/485 (30%)
		ERAP1_C	628..955	CDD:463368	84/335 (25%)