Protein Alignment CG31233 and AAP1

DIOPT Version :10

• Sequence 1: NP_732653.2
• Gene: CG31233 / 42557
• FlyBaseID: FBgn0051233
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_011913.1
• Gene: AAP1 / 856443
• SGDID: S000001089
• Length: 856
• Species: Saccharomyces cerevisiae
• Alignment Length: 921
• Identity: 242/921 - (26%)
• Similarity: 412/921 - (44%)
• Gaps: 130/921 - (14%)

  Fly    58 LPYDTIPSHYAVSLSTNVHTGDTVFNGTVAITLSV----LNTT----TKIVVHARQLENFTASII 114
            ||.:..|.||.::|..|...  ..|.|::.|.|.:    :|:.    .:|..|:.::|...|..:
Yeast     6 LPNNVTPLHYDITLEPNFRA--FTFEGSLKIDLQINDHSINSVQINYLEIDFHSARIEGVNAIEV 68

  Fly   115 QQGVTEAVAQELVYEYEAEREFLTFSKTGLTFPEDT------TWILTINYQGHLRTDNGGFYLST 173
            .:...:                   .|..|.||..|      :..|.|.:.|.|.....|||.:.
Yeast    69 NKNENQ-------------------QKATLVFPNGTFENLGPSAKLEIIFSGILNDQMAGFYRAK 114

  Fly   174 YTDE-EGNTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVDSSST---S 234
            |||: .|.|||:||||.|:||||.||||:|||:.:|.|.:|:..:.....:|||.|.:.:.   .
Yeast   115 YTDKVTGETKYMATTQMEATDARRAFPCFDEPNLKATFAVTLVSESFLTHLSNMDVRNETIKEGK 179

  Fly   235 GVTVFQKTVNMPSYLVAFIVSEFVFSEGELNGLPQRVFSRNGTEHEQEWALTTGMLVEKRLSGYF 299
            ..|.|..|..|.:|||||||::..:.|.....:|.||:|..|.|...::|........:.....|
Yeast   180 KYTTFNTTPKMSTYLVAFIVADLRYVESNNFRIPVRVYSTPGDEKFGQFAANLAARTLRFFEDTF 244

  Fly   300 DVPFALPKLDQAGIPDFAAGAMENWGLATYREEYLLYNTENSTTSTQTNIATIEAHEDAHMWFGD 364
            ::.:.|||:|...:.:|:|||||||||.|||...||.:.|||:......:|.:..||.||.|||:
Yeast   245 NIEYPLPKMDMVAVHEFSAGAMENWGLVTYRVIDLLLDIENSSLDRIQRVAEVIQHELAHQWFGN 309

  Fly   365 LVAIEWWSFLWLKEGFATLFENLAVDLAYPEWDIFQTFHAGSYQSALVNDASANARPMSHFVQKP 429
            ||.::||..|||.|||||.....:.:...|||.:::.:...:.|.||..|:..::.|:...|...
Yeast   310 LVTMDWWEGLWLNEGFATWMSWYSCNKFQPEWKVWEQYVTDNLQRALNLDSLRSSHPIEVPVNNA 374

  Fly   430 SEIALLYDSVSYAKAGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAANPSKLFEAIAKAAVEENY 494
            .||..::|::||:|..|:|.|....|....|.:|:..||...::..|....|::|:|.|:.::
Yeast   375 DEINQIFDAISYSKGSSLLRMISKWLGEETFIKGVSQYLNKFKYGNAKTGDLWDALADASGKD-- 437

  Fly   495 EVKATVPDMMGSWTNQGGVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDKLWYVPINYAESKNPD 559
                 |..:|..||.:.|.|:|:|..:.:..:.|..:.:.|.|.....|...| ||..|...:..
Yeast   438 -----VCSVMNIWTKRVGFPVLSVKEHKNKITLTQHRYLSTGDVKEEEDTTIY-PILLALKDSTG 496

  Fly   560 FRNTEATHYLLNQSEITIYSDLDQTNWLILNKKSTGYYRVLYDAQNYQLITSALITRPHKIDPRN 624
            ..||    .:||:...|.  :|....:..:|...:|.:...|..:.:    :.|..:.:.:...:
Yeast   497 IDNT----LVLNEKSATF--ELKNEEFFKINGDQSGIFITSYSDERW----AKLSKQANLLSVED 551

  Fly   625 RAQLINDLYRFATSGRVPHATLLELLTYLPQEDQYSPW-SATNTVITLLNRYLSGDADYGN-FQF 687
            |..|:.|....:.||.......|.|::....||.:..| ...|::..|.:.::....|..| ...
Yeast   552 RVGLVADAKALSASGYTSTTNFLNLISNWKNEDSFVVWEQIINSLSALKSTWVFEPEDILNALDK 616

  Fly   688 YVRELVSLQFDKFGVNDNKGDHHLVPFTRNVLINLACLAGLENCLTETTAKLTALVEEGTKIEPN 752
            :..:||..:..:.|.|..:.|...:...:..|.:.||.:|.|        |:.::..|
Yeast   617 FTLDLVLNKLSELGWNIGEDDSFAIQRLKVTLFSAACTSGNE--------KMQSIAVE------- 666

  Fly   753 LQSQVYCNGLKQA-----------------DDKTFDFVFNKLLNSTDQAERRLLISALGCSQNTA 800
             ..:.|.||.|||                 .:..::.:||...|.....|:.:.:.|||..::..
Yeast   667 -MFEEYANGNKQAIPALFKAVVFNTVARLGGENNYEKIFNIYQNPVSSEEKIIALRALGRFEDKE 730

  Fly   801 QLEKFVYSSIEPEGLRDQERITVLSPVYSRGEVGLLV---AIE----FLQKNWEKYG-QLNSG-- 855
            .||:.:...::.         |||:..:.....|:.|   .||    ::|::|::.. :|..|
Yeast   731 LLERTLSYLLDG---------TVLNQDFYIPMQGIRVHKKGIERLWAWMQEHWDEIAKRLQPGSP 786

  Fly   856 -FGGVNPLYSDIVGISAYTVNDKQKDALQELV-----DTVKGSEYVPSTLQDSVDSNVNANYAWL 914
             .|||..|     |::.:|    ..:||:::.     ...||.:   .||..::|: :.:...|:
Yeast   787 VLGGVLTL-----GLTNFT----SFEALEKISAFYSRKVTKGFD---QTLAQALDT-IRSKAQWV 838

  Fly   915 ASNRDPLMTWV 925
            :.:|:.:.|::
Yeast   839 SRDREIVATYL 849

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31233	NP_732653.2	M1_APN-Q_like	65..509	CDD:341064	148/461 (32%)
		ERAP1_C	586..905	CDD:463368	68/353 (19%)
AAP1	NP_011913.1	M1_APN-Q_like	13..447	CDD:341064	148/461 (32%)
		ERAP1_C	517..833	CDD:463368	69/357 (19%)