Protein Alignment CG31233 and Enpep

DIOPT Version :10

• Sequence 1: NP_732653.2
• Gene: CG31233 / 42557
• FlyBaseID: FBgn0051233
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_071587.2
• Gene: Enpep / 64017
• RGDID: 621228
• Length: 945
• Species: Rattus norvegicus
• Alignment Length: 966
• Identity: 263/966 - (27%)
• Similarity: 443/966 - (45%)
• Gaps: 92/966 - (9%)

  Fly     3 CVQVGGMSVFLVLLLAISATQAAVVRQYPILD----HLQHLENPMQRLVVPLADED-----NYRL 58
            |..|  ::|.|::.|::..|::......|...    |......|..:.|.|.:|::     |:||
  Rat    23 CATV--VAVGLIVGLSVGLTRSCEPGTTPAPSNPPPHTSTALPPQDQNVCPDSDDESGEWKNFRL 85

  Fly    59 PYDTIPSHYAVSLSTNVHTGDTVFNGTVAITLSVLNTTTKIVVHARQLENFTASIIQQGVTEAVA 123
            |....|.||  .|...|...:..:.|.|:|::::...|..:.:|.|:........:::...|.|.
  Rat    86 PDFIQPVHY--DLEVKVLMEEDRYTGIVSISVNLSKDTRDLWLHIRETRITKLPELRRPSGEQVP 148

  Fly   124 QELVYEYEAEREFLTFSKTGLTFPE-DTTWILTINYQGHLRTDNGGFYLSTYTDEEGNTKYLATT 187
            ....:||:.:...:..::..|.... |:.:.|||.::|.|.....|||.:||| |:|.||.:|.|
  Rat   149 IRRCFEYKKQEYVVIQAEEDLAATSGDSVYRLTIEFEGWLNGSLVGFYRTTYT-EDGQTKSIAAT 212

  Fly   188 QFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVDSSSTSG----VTVFQKTVNMPSY 248
            ..|.||||.:|||:|||:|:|.:.|::.|...|:|:|||||:...|..    .|.|.|:|.|.:|
  Rat   213 DHEPTDARKSFPCFDEPNKKATYNISLIHPKEYSALSNMPVEKEETLDNDWKKTTFMKSVPMSTY 277

  Fly   249 LVAFIVSEFV-FSEGELNGLPQRVFSRNGTEHEQEWALTTGMLVEKRLSGYFDVPFALPKLDQAG 312
            ||.|.|.:|. ......:|.|..|:.:...:...|:|......|......||.:.::|||||:..
  Rat   278 LVCFAVHQFTSIQRTSRSGKPLTVYVQPNQKQTAEYAANITKAVFDFFEDYFAMEYSLPKLDKIA 342

  Fly   313 IPDFAAGAMENWGLATYREEYLLYNTENSTTSTQTNIATIEAHEDAHMWFGDLVAIEWWSFLWLK 377
            ||||..||||||||.||||..|||:...|.:|.|..:|::.|||..|.|||::|.::||..|||.
  Rat   343 IPDFGTGAMENWGLVTYRETNLLYDPLLSASSNQQRVASVVAHELVHQWFGNIVTMDWWDDLWLN 407

  Fly   378 EGFATLFENLAVDLAYPEWDIFQTFHAGSYQSALVNDASANARPMSHFVQKPSEIALLYDSVSYA 442
            ||||:.||.|.|:.|..:|.:..............:|:..::.|:...|..|:||..::|.:||:
  Rat   408 EGFASFFEFLGVNHAEADWQMLSQVLLEDVLPVQEDDSLMSSHPVVVTVSTPAEITSVFDGISYS 472

  Fly   443 KAGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAANPSKLFEAIAKAAVEENYEVKATVPDMMGSW 507
            |..|:|.|.:..:|...||:|...||.:.:|..|..|..::::.||:   |..||    ::|.:|
  Rat   473 KGASILRMLQDWITPEKFQKGCQIYLENFKFKNAKTSDFWDSLEKAS---NQPVK----EVMDTW 530

  Fly   508 TNQGGVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDK---------LWYVPINYAESKNPDFRNT 563
            |:|.|.|::||     :|...|.|..:.  .||..|.         .|.:||.:.|:.|.:.
  Rat   531 TSQMGYPVVTV-----SGKQNVTQKRFL--LDYKADPSQPPSALGYTWNIPIKWTENGNSNI--- 585

  Fly   564 EATHYLLNQSEITIYSDLDQTNWLILNKKSTGYYRVLYDAQNYQLITSALITRPHKIDPRNRAQL 628
             ..:|..|:..||:.::|....:|.:|....|:|||.|:|:.:..|...|.:........:|:..
  Rat   586 -TVYYRSNREGITLNANLSGDGFLKINPDHIGFYRVNYEAETWDWIAETLSSNHMNFSSADRSSF 649

  Fly   629 INDLYRFATSGRVPHATLLELLTYLPQEDQYSPWSATNTVITLLNRYLSGDAD-YGNFQFYVREL 692
            |:|.:..|.:..:.:...|.|..||..|..:.||....:.::.:......|.: |...:.|.|..
  Rat   650 IDDAFALARAQLLDYEKALNLTRYLTSEKDFLPWERVISAVSYIISMFEDDRELYPLIETYFRSQ 714

  Fly   693 VSLQFDKFGVNDNKGDHHLVPFTRNVLINLACLAGLENCLTETTAKLTALVEEGTKIEPNLQSQV 757
            |....|..|..|.  ..|:....|..::..||..|....|...:....|.::....|..||:..|
  Rat   715 VKPIADSLGWQDT--GSHITKLLRASVLGFACKMGAGEALGNASQLFEAWLKGNESIPVNLRLLV 777

  Fly   758 YCNGLKQA-DDKTFDFVFNKLLNSTDQAERRLLISALGCSQNTAQLEKFVYSSIEPEGLRDQERI 821
            |..|::.: ::..:::...:...::...|:..|:..|...::...|.:::....:|..::.|:..
  Rat   778 YRYGMQNSGNEAAWNYTLEQYQKTSLAQEKEKLLYGLASVKDVTLLARYLEMLKDPNIIKTQDVF 842

  Fly   822 TVLSPVYSRGEVGLLVAIEFLQKNWEKYGQLNSGFGGVNPLYSDIVGISAYTVNDKQKDALQELV 886
            ||:..: |....|..:|..::|.||:..                   ::.:|:||:....:..:.
  Rat   843 TVIRYI-SYNSYGKSMAWNWIQLNWDYL-------------------VNRFTINDRYLGRIVTIA 887

  Fly   887 DTVK------------------GSEYVPSTLQDSVDSNVNANYAWLASNRDPLMTW 924
            :...                  |:...|   ::.|...|..|..||..||..:..|
  Rat   888 EPFNTELQLWQMQSFFAKYPNAGAGAKP---REQVLETVKNNIEWLKLNRKSISEW 940

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31233	NP_732653.2	M1_APN-Q_like	65..509	CDD:341064	155/449 (35%)
		ERAP1_C	586..905	CDD:463368	62/338 (18%)
Enpep	NP_071587.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	45..77		6/31 (19%)
		M1_APN-Q_like	92..531	CDD:341064	154/448 (34%)
		ERAP1_C	607..925	CDD:463368	63/342 (18%)