Protein Alignment CG31233 and RNPEP

DIOPT Version :10

• Sequence 1: NP_732653.2
• Gene: CG31233 / 42557
• FlyBaseID: FBgn0051233
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_064601.3
• Gene: RNPEP / 6051
• HGNCID: 10078
• Length: 650
• Species: Homo sapiens
• Alignment Length: 509
• Identity: 111/509 - (21%)
• Similarity: 166/509 - (32%)
• Gaps: 142/509 - (27%)

  Fly   179 GNTKYLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNMPVDSSSTSGVTVFQKTV 243
            |..|....||.::...|..|||:|.|:.:.:::..|:....:.|:.:.............||...
Human   160 GKKKPFVYTQGQAVLNRAFFPCFDTPAVKYKYSALIEVPDGFTAVMSASTWEKRGPNKFFFQMCQ 224

  Fly   244 NMPSYLVAFIVSEFVFSEGELNGLPQRVFSR-----------NGTEHEQEWALTTGMLVEKRLSG 297
            .:||||:|..:.:.|.:|   .|...||::.           ||...|   .|.||   ||....
Human   225 PIPSYLIALAIGDLVSAE---VGPRSRVWAEPCLIDAAKEEYNGVIEE---FLATG---EKLFGP 280

  Fly   298 Y----FDVPFALPKLDQAGIPDFAAGAMENWGLATYREEYLLYNTENSTTSTQTNIATIEAHEDA 358
            |    :|:.| :|       |.|..|.|||..| |:....||        :...::|.:..||.:
Human   281 YVWGRYDLLF-MP-------PSFPFGGMENPCL-TFVTPCLL--------AGDRSLADVIIHEIS 328

  Fly   359 HMWFGDLVAIEWWSFLWLKEGF--------------------------ATLFENLAV-------- 389
            |.|||:||....|...||.|||                          |.|.:::.:
Human   329 HSWFGNLVTNANWGEFWLNEGFTMYAQRRISTILFGAAYTCLEAATGRALLRQHMDITGEENPLN 393

  Fly   390 ------------DLAYPEWDIFQTFHAGSYQSALVNDASANARPMSHFVQKPSEIALLYDS---- 438
                        |..|.|....:.|...||.:.||.|.......:..:|.:....::|.|.
Human   394 KLRVKIEPGVDPDDTYNETPYEKGFCFVSYLAHLVGDQDQFDSFLKAYVHEFKFRSILADDFLDF 458

  Fly   439 -VSYAK----------AGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAANPS----KLFEAIAKA 488
             :.|..          .|...|.|    .||   .|...||.|     .:|.    |..|.:|:.
Human   459 YLEYFPELKKKRVDIIPGFEFDRW----LNT---PGWPPYLPD-----LSPGDSLMKPAEELAQL 511

  Fly   489 AVEENYEVKATVPDMMGSWTNQGGVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDKLWYVPINYA 553
            ...|..::||.....:..|            :.|        |.||..||......|....:...
Human   512 WAAEELDMKAIEAVAISPW------------KTY--------QLVYFLDKILQKSPLPPGNVKKL 556

  Fly   554 ESKNPDFRNTEATHYLLNQSEITIYSDLDQTNW----LILNKKSTGYYRVLYDA 603
            ....|...|.......|...:|.:.:|..:..|    .:.|:....|...||.|
Human   557 GDTYPSISNARNAELRLRWGQIVLKNDHQEDFWKVKEFLHNQGKQKYTLPLYHA 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31233	NP_732653.2	M1_APN-Q_like	65..509	CDD:341064	93/409 (23%)
		ERAP1_C	586..905	CDD:463368	6/22 (27%)
RNPEP	NP_064601.3	M1_LTA4H	24..484	CDD:341062	79/353 (22%)
		Leuk-A4-hydro_C	530..644	CDD:462686	19/101 (19%)