Protein Alignment CG31233 and Lta4h

DIOPT Version :10

• Sequence 1: NP_732653.2
• Gene: CG31233 / 42557
• FlyBaseID: FBgn0051233
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_001025202.1
• Gene: Lta4h / 299732
• RGDID: 1311333
• Length: 611
• Species: Rattus norvegicus
• Alignment Length: 623
• Identity: 130/623 - (20%)
• Similarity: 209/623 - (33%)
• Gaps: 190/623 - (30%)

  Fly    71 LSTNVHTGDTVFNGTVAITLSVLN-------------TTTKIVVHARQL-------ENFTASIIQ 115
            |..:|........||.|:|:....             |..|:|::.:::       :.:..|.::
  Rat    24 LRCSVDFARRALTGTAALTVQSQEDNLRSLTLDTKDLTIEKVVINGQEVKYTLGESQGYKGSPME 88

  Fly   116 QGVTEAVA--QELVYEYEAEREFLTFSKTGLTFPEDTT--WILTINYQGHLRTDNGGFYLSTYTD 176
            ..:..|::  ||:|.|...|           |.|:.:.  |:                     |.
  Rat    89 ISLPIALSKNQEVVIEISFE-----------TSPKSSALQWL---------------------TP 121

  Fly   177 EEGNTK---YLATTQFESTDARHAFPCYDEPSKRAEFTITIKHDPSYNAISNM--------PVDS 230
            |:.:.|   || .:|.::...|...||.|.||.:..:|..:.......|:.:.        |.|.
  Rat   122 EQTSGKQHPYL-FSQCQAIHCRAILPCQDTPSVKLTYTAEVSVPKELVALMSAIRDGEAPDPEDP 185

  Fly   231 SSTSGVTVFQKTVNMPSYLVAFIVSEFVFSEGELNGLPQRVFSRNGTEHEQ------EWALTTGM 289
            |..  :..|.:.|.:|.||:|.:|...   |....|....|:|    |.||      |::.|..|
  Rat   186 SRK--IYRFNQRVPIPCYLIALVVGAL---ESRQIGPRTLVWS----EKEQVEKSAYEFSETESM 241

  Fly   290 L-VEKRLSGYFDVPFALPKLDQAGI-PDFAAGAMENWGLATYREEYLLYNTENSTTSTQTNIATI 352
            | :.:.|.|    |:...:.|...: |.|..|.|||..| |:....||        :...:::.:
  Rat   242 LKIAEDLGG----PYVWGQYDLLVLPPSFPYGGMENPCL-TFVTPTLL--------AGDKSLSNV 293

  Fly   353 EAHEDAHMWFGDLVAIEWWSFLWLKEGFATLFENLAVDLAYPEWDIFQTFHA----GSYQSALVN 413
            .|||.:|.|.|:||..:.|...||.||.....|.......:.|  .|:.|||    |..|:.:
  Rat   294 IAHEISHSWTGNLVTNKTWDHFWLNEGHTVYLERHICGRLFGE--KFRHFHALGGWGELQNTI-- 354

  Fly   414 DASANARPMSHFV--QKPSEIALLYDSVSYAKAGSVLDMWRHALTNTVFQRGLHNYLVDNQFTAA 476
            .....:.|.:..|  .|..:..:.|.|:.|.|..::|......|                    .
  Rat   355 KTFGESHPFTKLVVDLKDVDPDVAYSSIPYEKGFALLFYLEQLL--------------------G 399

  Fly   477 NPSKLFEAIAKAAVEENYEVKATVPDM-------------------MGSWTNQGGVPLLTVTRNY 522
            .| ::|....||.||:......|..|.                   ..:|....|:|  .|..||
  Rat   400 GP-EVFLGFLKAYVEKFSYQSVTTDDWKSFLYAHFKDKVDLLNQVDWNAWLYAPGLP--PVKPNY 461

  Fly   523 D----NGSFTVKQSVYTNDKDYTNDKLWYVPINYAESKNPDFRNTEATHYLLNQSEITIYSDLD- 582
            |    |....:.|                   .:..:|..|          ||...|....||.
  Rat   462 DVTLTNACIALSQ-------------------RWVTAKEED----------LNSFSIEDLKDLSS 497

  Fly   583 -QTNWL---ILNKK--STGYYRVLYDAQNYQLITSALI 614
             |.|..   :|.|.  ..|:.:.:.:..|:..|.::.|
  Rat   498 HQLNEFLAQVLQKAPLPLGHIKRMQEVYNFNAINNSEI 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31233	NP_732653.2	M1_APN-Q_like	65..509	CDD:341064	107/505 (21%)
		ERAP1_C	586..905	CDD:463368	6/34 (18%)
Lta4h	NP_001025202.1	leuko_A4_hydro	6..608	CDD:274120	130/623 (21%)