Protein Alignment CG31233 and T16G12.1

DIOPT Version :10

• Sequence 1: NP_732653.2
• Gene: CG31233 / 42557
• FlyBaseID: FBgn0051233
• Length: 952
• Species: Drosophila melanogaster
• Sequence 2: NP_499230.2
• Gene: T16G12.1 / 176416
• WormBaseID: WBGene00011803
• Length: 1890
• Species: Caenorhabditis elegans
• Alignment Length: 998
• Identity: 253/998 - (25%)
• Similarity: 401/998 - (40%)
• Gaps: 234/998 - (23%)

  Fly    57 RLPYDTIPS------HYAVSLSTNVHTG-------DTVFNGTVAITLSVLNTTTKIVVHARQLEN 108
            :.|::..|:      :|.:.|..|:...       :..|:.|..:|..:::.|:.|.::|.:|
 Worm   989 KTPWEKTPNIDAVFPYYKLDLQVNIPGSGPYQWYENMTFSATSTVTFQLVSPTSSITINAHRL-- 1051

  Fly   109 FTASIIQQGVTEAVAQELVYEYEAEREF---LTFSKTGLTFPEDTTWILTIN------------- 157
                     :.:.|:..|..|.:.....   :.|||....:.:.|..|.|:|
 Worm  1052 ---------MFDPVSIRLYNENDENAHTPIPIDFSKVMKDYDKGTVTIPTMNNTVLYPNQYSLFI 1107

  Fly   158 -YQGHL-RTDNGGFYLSTYTDEEGNTK-YLATTQFE-STDARHAFPCYDEPSKRAEFTITIKHDP 218
             |.|.: :..:.|...:||.....|.| ::.||.|| ...||...||:||||.:.:|.:::.|..
 Worm  1108 EYTGFIFQNPDEGDASNTYLGGLNNRKGWIFTTDFEGGPGARSLLPCWDEPSYKGQFEVSVFHPT 1172

  Fly   219 SYNAISNMPVDSSST---SG--VTVFQKTVNMPSYLVAFIVSEFV-FSEGELNGLPQRVFSRNGT 277
            ...|:|| .||...|   :|  .|.|..|..|.:||:|..|..|. .:.....|:..||::.:|.
 Worm  1173 DMIALSN-EVDIQRTIYDNGWTTTKFATTNQMSTYLLALCVGHFSNLATVTRTGVLTRVWTWSGM 1236

  Fly   278 EHEQEWAL--TTGMLVEKRLSGYFDVPFALPKLDQAGIPDFA--AGAMENWGLATYREEYLLYNT 338
            |...|:||  |.|.:  ..:..||...|.|.|||...:|::.  |||||||||........:::.
 Worm  1237 EQYGEFALNVTAGTI--DFMENYFSYDFPLKKLDVMALPEYTMNAGAMENWGLIIGEYSLFMFDP 1299

  Fly   339 ENSTTSTQTNIATIEAHEDAHMWFGDLVAIEWWSFLWLKEGFATLFENLAVDLAYPEWDIFQTFH 403
            :.:||...|.:|...|||..|.||||:|.::||:.::|.||||..:....:|..:||...:...:
 Worm  1300 DYATTRDITEVAETTAHEVVHQWFGDIVTLDWWNDIFLNEGFAQYWFANGIDNTFPEQHAYSIDY 1364

  Fly   404 AGSYQSALVNDASANARPMSHFVQKPSEIALLYDSV------------------SYAKAGSVLDM 450
            ...|              |:|       |||.||.:                  .|.|..::|::
 Worm  1365 NRFY--------------MNH-------IALKYDCIPGVAKPVISDTPPVFGIEPYYKGSALLNL 1408

  Fly   451 WRHALTNTVFQRGLHNYLVDNQFTAANPSKLFEAIAKAAVEENYE----VKATVPDMMGSWTNQG 511
            ..:.||..|||.||.:||....:..|:|..|:.::..||...|..    ....|...|..:|.|.
 Worm  1409 LNNVLTPAVFQEGLSSYLTQYGYVNASPRNLWTSLTVAAQRHNITDWNGQPLDVSSFMDPYTLQT 1473

  Fly   512 GVPLLTVTRNYDNGSFTVKQSVYTNDKDYTNDK-LWYVPINYAESKNPDFRNTEATHYLLNQSEI 575
            ..|::|:|.   .|:.||:    .|.:...:|: ||.||:........||      ::.:|
 Worm  1474 SYPIITLTL---RGTSTVQ----ANQQSCMSDETLWNVPLFTQTPGALDF------NWFVN---- 1521

  Fly   576 TIYSDLDQTNWL--------ILNKKSTGYYRVLYDAQNYQLITSALITRPHKIDPRNRAQLINDL 632
              ::..:...||        :.|..||.:.|:.||.:::..|.:.|::..:.:....||.|::|.
 Worm  1522 --FTGGNDATWLRPLPTGYRVDNAGSTSFARINYDDKSWYSIQAQLLSNMNTMSSTTRAMLLDDA 1584

  Fly   633 YRFATSGRVPHATLLELLTYLPQEDQYSPWSATNTVIT-LLNRYLSGDADYGNFQFYVRELVSLQ 696
            ..|..|||......|:|..||..||..:||.......| :|||: ....:....:.||.::....
 Worm  1585 NFFYQSGRWEMTKFLDLTLYLVNEDSLAPWEQAIEFFTEMLNRF-QYQPEIDTVRNYVIQITKNA 1648

  Fly   697 FDKFGVNDN---KGDH--HLVPFTRNVLIN---------------LAC---LAGLENCLTETTAK 738
            ..||..|.|   ..|.  .|:....|:.:|               |.|   |:|...|
 Worm  1649 VSKFQWNTNGLWANDRIVQLLVNVNNLAVNRQSRQVALTLFNNFVLKCKYSLSGTGKC------- 1706

  Fly   739 LTALVEEGTKIEPNLQSQVYCNGLKQA---DDKTFD------FVFNKLLNSTDQAERRLLISALG 794
                    :.|.|||:...||.||:|:   ||.|..      ||.|.....||.:.   |::|||
 Worm  1707 --------SGIHPNLRQPTYCYGLRQSNNIDDFTTVNNLYSWFVQNAGYLQTDGSN---LLNALG 1760

  Fly   795 CSQNTAQLEKFVYSSI----EPEGLRDQERI-----------------TVLSPVYSRGEVGLLVA 838
            |.|| ..|:|.:..||    .|..|.:...:                 .:|:..:   :..|.|.
 Worm  1761 CVQN-LDLQKTMLRSILSGDYPPSLLNSIAVHDDSSDVLYNFLLDNTQDILNAPF---DFSLYVK 1821

  Fly   839 IEFLQKNWEKYGQLNSGFGGVNPLYSDIVGISAYT-VNDKQKDALQELVDTVKGSEYVPSTLQDS 902
            ..|  :||....||.        |..|....|.|. :|..||:..::.:.||
 Worm  1822 AMF--QNWSTSNQLE--------LAKDFQNSSNYNLLNAAQKNIYKQGILTV------------- 1863

  Fly   903 VDSNVNANYAWLASNRDPLMTWV 925
               |.|||  |:...:.|.:.|:
 Worm  1864 ---NSNAN--WMLIYKTPFLEWI 1881

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG31233	NP_732653.2	M1_APN-Q_like	65..509	CDD:341064	135/508 (27%)
		ERAP1_C	586..905	CDD:463368	92/381 (24%)
T16G12.1	NP_499230.2	M1_APN-Q_like	90..544	CDD:341064
		ERAP1_C	639..931	CDD:463368
		M1_APN-Q_like	1005..1471	CDD:341064	135/500 (27%)
		ERAP1_C	1542..1839	CDD:463368	82/329 (25%)