Protein Alignment CG5849 and SP1029

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: NP_652618.1
• Gene: SP1029 / 53473
• FlyBaseID: FBgn0263236
• Length: 932
• Species: Drosophila melanogaster
• Alignment Length: 945
• Identity: 257/945 - (27%)
• Similarity: 433/945 - (45%)
• Gaps: 129/945 - (13%)

  Fly     9 VVLVTLGLLVSGSMGERERS----LRLPNATYPLFYQLHISSDIHKGQ-LLFSGNATIDVAIRQS 68
            |..:.|||..:.|..:...:    .|||.:..|..|.|.|.:.:...: |.|||:..|.:...::
  Fly     8 VAALGLGLATADSSADSIETTYNYYRLPTSLRPQKYHLRILTLLENPEDLRFSGSVKILIEALEN 72

  Fly    69 TNEIVLHAKNLT--DIQITVHRLMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLE 131
            |..:.||:||||  :.|||:.::..||.:.....:..::|:....|::..:...|   |..|.|.
  Fly    73 TKNVTLHSKNLTIDESQITLRQIGGEGKKENCVSSTAVNPSHDFYILNTCQELLA---GNTYELY 134

  Fly   132 ILYTAIMASRPAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSS 196
            :.:.|.:..:..|.|...|:|...|.|.:::.||.||...||.|||:|||.||:.|.:.:.:...
  Fly   135 MPFAADLNRQLEGYYRSSYKDPVANLTKWISVTQFEPASARLAFPCFDEPDFKAPFVVTLGYHKK 199

  Fly   197 HSAISNMPVKEVLAH---GDLKTTSFHTTPPISTYLVAFVISDFGSISET------YRGITQSIY 252
            ::||||||.||...|   .|.....|..:.|:||||||:.::||.....|      :|     .:
  Fly   200 YTAISNMPEKETKPHETLADYIWCEFQESVPMSTYLVAYSVNDFSHKPSTLPNSALFR-----TW 259

  Fly   253 TSPTSKEKGQVALKNAVRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLITYKDVNLLKN 317
            ..|.:.::...|.:...:.:...|.:||:.:||||:|.:|:......|||||||:||:::.||.:
  Fly   260 ARPNAIDQCDYAAQFGPKVLQYYEQFFGIKFPLPKIDQIAVPDFSAGAMENWGLVTYREIALLYS 324

  Fly   318 I--SSDGQKRKLDLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDM 380
            .  ||...|:::..:.. ||:|||||||||:.:|||..|:|||||||.:.:..:.|.|..:.|:.
  Fly   325 AAHSSLADKQRVASVVA-HELAHQWFGNLVTMKWWTDLWLNEGFATYVASLGVENINPEWRSMEQ 388

  Fly   381 FMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISH 445
            .......:.:..::....||:|..::...:|...||.|||::|:.|::|.|....::.|..|:..
  Fly   389 ESLSNLLTIFRRDALESSHPISRPIQMVSEISESFDQISYQKGSTVLRMMHLFLGEESFRSGLQA 453

  Fly   446 FLEKYRYSVANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTI 510
            :|:|:.|..|.:.||:::|   .|....:...|.:..|:.||.|||.....|::.|||:|...|.
  Fly   454 YLQKFSYKNAEQDNLWESL---TQAAHKYRSLPKSYDIKSIMDSWTLQTGYPVINVTRDYAARTA 515

  Fly   511 TFTQRSVHMKDEL--------WWIPINFATTQSPNFEDTQVDMFMP--------PQPQYTVSLED 559
            ...|....:..::        ||:|:::.|....:|.:|....:|.        |:     :::|
  Fly   516 KLNQERYLLNTQVARAYRGGCWWVPLSYTTQAVQDFNNTAPKAWMECGKNGESLPK-----TIQD 575

  Fly   560 LNIHVSGRD-WIMVNKQHTGFYLVRYDTDNLMAIARQLQTNHSV--IHPINRLGLFRDLGPLIEH 621
            |    .|.| |::.|.|.:..|.|.||..|...:...| ||...  ||.|||..|..|...|...
  Fly   576 L----PGPDQWVIFNTQLSTLYKVNYDAQNWKLLIETL-TNGDFERIHVINRAQLIDDALYLAWT 635

  Fly   622 NEIEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYV 686
            .| :..|:...|::||:.|.:.|.|....:.::.:.|.:..|.....|..::::|:.|.:..:
  Fly   636 GE-QDYEIAMRLIEYLQREREYLPWKSAFENLKRVGRIVRQTPDFEFFKRYMKKLILPIYEHL-- 697

  Fly   687 EQGVNLAEDGMFRGI------------LEIACSAD----LPECLEYTRRLAKEHIIDKIYFKDGS 735
             .|:|    ..|..|            :..||...    :|:.|.|.|....|...|:   |:..
  Fly   698 -NGIN----DTFSAIPQQDQVLLKTMVVNWACQYQVGDCVPQALAYYRNWRAEANPDE---KNPV 754

  Fly   736 DYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYL------ 794
            ..: :..:|.|..:::.||.|::.:....:: ...:.....|:.||.|::....|..||
  Fly   755 PIN-VRSTVYCTSIKHGSDSDWEFLWTRYKK-SNVAAEKRTILTALGCSREVWLLQRYLELTFDP 817

  Fly   795 -EGLMGENSTHMVLS-EFEDLMYLL----------YIYK---------SNLASRPVIWQYIERNY 838
             |.:..::|.....: .|.::.:||          :|||         |.|.| |:..|.|.
  Fly   818 KEAIRKQDSMWAFQAVAFNEVGFLLAKKYFMDNVDFIYKFYHPLTKDMSRLLS-PLSEQVIT--- 878

  Fly   839 KVLCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTI 873
                     |..|.:...|| .:.|...:.|.|.|
  Fly   879 ---------LSDFNEFKDFV-NNSRQSLKGLEQAI 903

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	149/467 (32%)
		ERAP1_C	569..841	CDD:463368	71/316 (22%)
SP1029	NP_652618.1	M1_APN-Q_like	42..497	CDD:341064	149/466 (32%)
		ERAP1_C	582..910	CDD:463368	79/350 (23%)