Protein Alignment CG5849 and lnpep

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: XP_021331685.2
• Gene: lnpep / 322814
• ZFINID: ZDB-GENE-030131-1534
• Length: 1025
• Species: Danio rerio
• Alignment Length: 917
• Identity: 235/917 - (25%)
• Similarity: 406/917 - (44%)
• Gaps: 127/917 - (13%)

  Fly    29 LRLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDIQITVHRLMAEG 93
            ||||.:.:|:.|.:.:..|::  .:.|.||.:|.|.:...|..||||:.::..|::|
Zfish   176 LRLPVSVHPVHYNISLHPDLN--SMTFQGNVSIVVLVVHETKNIVLHSSDMNIIKVT-------- 230

  Fly    94 SEIVDDLTHTL---HPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASRPAGLYYMDYRDEEN 155
               .||..:..   .|...:.|..|    :..::| ||.|:..|.|.:::...|.|...|.|...
Zfish   231 ---FDDKEYRFLEYKPWQQIAIKFP----EDLKKG-QYVLKFSYKANLSNSYDGFYNSSYVDTAG 287

  Fly   156 NHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAISNMP-VKEV-LAHGDLKTTS 218
            ...| :||||.||...|..|||:|||.|||.|.:|:|..:.:.::|||| :|.. |....|:...
Zfish   288 TKRV-LAATQFEPLAARKAFPCFDEPAFKSTFVVKMTREAKYISLSNMPKIKTTDLNENGLQEDE 351

  Fly   219 FHTTPPISTYLVAFVISDFGSISETYRGITQSIYTSPTSKEKGQVALKNAVRTVAALEDYFGVSY 283
            |.::..:|||||||::::|.|.|:.....|.|:|..|..|::...||:.|.:.:.....:|.:.|
Zfish   352 FESSVKMSTYLVAFIVAEFSSHSKNVSKTTVSVYAVPDKKDQVHYALETACKLLKFYNTFFEIEY 416

  Fly   284 PLPKLDHVALKKNYGAAMENWGLITYKDVNLLKNISSDGQKRKLDLITQNHEIAHQWFGNLVSPE 348
            ||.|||.||:......|||||||||:::..||....|....::|......||:|||||||||:..
Zfish   417 PLSKLDLVAIPDFLAGAMENWGLITFRETTLLVGNQSSRFDKQLVTSVIAHELAHQWFGNLVTMR 481

  Fly   349 WWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMG 413
            ||...|:|||||||..|:..:.::| |..:|:...:....|.:.::....||:|.:|...:.:..
Zfish   482 WWNDLWLNEGFATYMQYMSIENVFP-DLDIDIEFLNVRFKALAKDALNSSHPVSTFVSTPEQVEE 545

  Fly   414 VFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYSVANELNLFDALHSELQDDEYFSHQP 478
            :||.:||::||.::.|.:...|...|.:|:..:|:.|..|.....:|:::|       ...|.|
Zfish   546 MFDSVSYEKGASILLMLNATLRDGEFHKGVIEYLQNYNLSNTESKDLWNSL-------SQVSKQ- 602

  Fly   479 WASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQRSVHMK------DELWWIPINF------- 530
             :..:.|:|.:||..:..|::.|.||  ...:|.:|....:.      |.||.||:.:
Zfish   603 -SLNVSEMMNTWTVHKGFPLVTVKRN--GPQVTLSQEHFLLNAENGTDDSLWHIPLTYVNDSCSV 664

  Fly   531 --ATTQSPNFEDTQVDMFMPPQPQYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDNLMAIA 593
              :..|..:.:|.:..:.:|.|.:                |:..|.:..|||:|.||......:.
Zfish   665 LRSCKQVFHLKDKEATLQLPGQVK----------------WLKFNFRSDGFYIVHYDEQGWSDLI 713

  Fly   594 RQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTR 658
            ..|:.:.:|:...::..|..::..|....:: ....|..|:.|:..|.:.....:....:..:.|
Zfish   714 SALKVDVNVLPSEDKAALINNIFALSRLGKV-SFRQVLNLMDYIRNETETAPLTEALSQLGQIYR 777

  Fly   659 NLHGTSSQSL---FNEFVRRLVGPTFRRVYVEQGVNLAEDGMFRGILEIACSADLPECLEYTRRL 720
            .|...|..:|   ...::....|........|...::::..:...:||.||:.:.|.|....|||
Zfish   778 LLDKRSDLNLASSMTTYIESHFGSLMESQSWEVETSVSKMTLRSALLETACALNRPNCTTQARRL 842

  Fly   721 AKEHIIDKIYFKDGSDYHAIIDSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDD---IIYALR 782
            ..:.:......:..||....:..|...     :|:.:.:::...:.    |:|..:   ::.||.
Zfish   843 FDQWLASNKTLQIPSDLMRTVFKVAAK-----TDEGWSKLLGSYKH----SIYDTEKRKMLEALA 898

  Fly   783 CTQSHRHLLYY----LEGLMGENS-----THMVLSEFEDLMYLLYIYKSNLASRPVIWQYIERNY 838
            .||..|.:::.    |:|...:|.     .|.|..:|...:|.....|.|       |:.|.:.:
Zfish   899 STQDVRKIIWVLQKSLDGSEIQNQEFPLVIHTVCRDFAGYLYAWDFMKEN-------WEKITQKF 956

  Fly   839 KV---------------------LCRAPNFLEHFKQLAGFVPRHQRSHFERLRQTIANHM--MQE 880
            .:                     |....||   |..|.  ....|....:...:||.::|  |::
Zfish   957 PIGSFAIQSIITSTTSQFSTKTHLAEVQNF---FSSLG--AKGSQMRIVQEAIETIKHNMRWMEK 1016

  Fly   881 GLNTNQT 887
            .|||.|:
Zfish  1017 NLNTLQS 1023

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	147/458 (32%)
		ERAP1_C	569..841	CDD:463368	53/307 (17%)
lnpep	XP_021331685.2	None