Protein Alignment CG5849 and LOC1272139

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: XP_311017.5
• Gene: LOC1272139 / 1272139
• VectorBaseID: AGAMI1_006784
• Length: 953
• Species: Anopheles gambiae
• Alignment Length: 1061
• Identity: 237/1061 - (22%)
• Similarity: 414/1061 - (39%)
• Gaps: 242/1061 - (22%)

  Fly     4 PPSGVVVLVTLGLLVSGSMGERER---------------SLRLPNATYPLFYQLHISSDIHKGQL 53
            |.|.|:|::.:.||..|...:..|               ..:||....|..|.||:...:.:.
Mosquito     5 PLSLVMVVLAIMLLPYGYTWKEYRIRRSIDLSAANPLISDTKLPTDLVPSGYSLHLHPVLDRS-- 67

  Fly    54 LFSGNATIDVAIRQSTNEIVLHAKN---LTDIQITVHRL-MAEGSEIVDDLTHTLHPTAALLIIH 114
            :|||...|.:...::||:|.|||.:   :.::::.|.|: .|||...|........|...||:|:
Mosquito    68 IFSGRVNITLLCAKATNQINLHAHHDLTVDELELEVVRIGGAEGGTKVPIRRVDRVPKKPLLVIY 132

  Fly   115 PIENYQAFEEGQQYRLEILYTAIMASRPAGLYYMDYRDEENNHTVYVAATQCE------------ 167
               .:.|...|..|.:.:.:...:.....|::...|:.:::......|.|:.|
Mosquito   133 ---FHDALTAGAAYEVRLRFVGNIWENVEGIFEGKYKQQQSTGPSEPAGTESEGVTEPEEHSFIG 194

  Fly   168 ----PTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAISNMPVKEVLAHGDLK--TTSFHTTPPIS 226
                |.:.|.:|||:|||.:|..|::.|....:|..:.|..::..:..||.|  ...|..|.|:|
Mosquito   195 TYFRPHHARRVFPCFDEPSYKVPFNVSIVRPRTHHVLFNTALERTVETGDGKHVIDVFKQTAPMS 259

  Fly   227 TYLVAFVISDFGSISETYRGITQSIYTSPTSKEKGQVALKNAVRTVA------------------ 273
            |:...|::||...:            |...|.||....||..:|..|
Mosquito   260 TFTFGFLVSDLQQV------------TPSLSDEKEDERLKPTIRVWARRDFQKNVADVQQRVKLA 312

  Fly   274 --ALEDYFGVSYPLPKLDHVALKK-NYGAAMENWGLITYKDVNLLKNISSDGQKRKLDLITQNHE 335
              .|::|:||..||.|||.|||.. :|....:|||||.:|:..|::...:..|           |
Mosquito   313 LRKLQEYWGVPLPLEKLDVVALPGFSYVKPADNWGLIVFKESELMRGYYNLAQ-----------E 366

  Fly   336 IAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDLIYPNDKMMDMFMTHEADSAYSY---NSFFD 397
            :.:||.|:.::|.||:...:|:..|.:.|                     ||:|...   :.|..
Mosquito   367 LVYQWLGSWITPHWWSDAHVNKAIAGFLS---------------------ADTAIKIDGGDEFEG 410

  Fly   398 VHPM----SHYVEGEK-----DIMGVFDIISYKRGACVIKMFHHAFRQKLFVRGISHFLEKYRYS 453
            .:||    |.|.|..|     .|..:....:..:...|::|.::...::.|.||:..|::...|.
Mosquito   411 KYPMTILYSIYYEFSKRYPHSRITAMKQETTCSKTELVLRMLNYTLGEETFRRGLQRFIQHREYK 475

  Fly   454 VANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILVVTRNYENNTITFTQR--- 515
            .....::::||..:...|:....   :..:.:::.||...:.:|::.|.|:|.|.|.|.|||
Mosquito   476 TFYGEDVWEALTKQAHLDQRLCE---SVTVNDVVNSWITKDRIPMVRVVRSYANRTATVTQRLYL 537

  Fly   516 -----SVHMKDE-LWWIPINFATTQSPNFEDTQVDMFMPPQPQYTVSLEDLNIHVSGRD-WIMVN 573
                 .|..:|: |||||:........||.:.....:|....:  |:|::|    .|.| :|:||
Mosquito   538 RERPHDVPEQDKMLWWIPLVVVRQDRLNFGNVSTIRWMKQVRE--VTLDEL----PGPDEFIIVN 596

  Fly   574 KQHTGFYLVRYDTD--NLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFELLKY 636
            .:..|.:.|.||..  ||:|...|.:.:.::|....|..|..|...|....:: .....|.:..:
Mosquito   597 PEEIGPFPVNYDERNWNLLATFLQKEESRTMIPVYTRAKLLHDAWNLAYAGDL-SFGTAFNMTLF 660

  Fly   637 LELEEDVLTWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRVYVEQGVNLAEDGMFRGI 701
            ::.|.:.|.||.:...|:.:.|::..::....|..:||.|:.|.:..:.   |.....:.|::..
Mosquito   661 MKYERNHLVWNPVFTLIDHIGRHIDMSAVHKKFEMYVRTLLTPLYEELV---GNQQESEEMWKAN 722

  Fly   702 L-----EIACSADLPECLEYTRRLAKEHIIDKIYFKDGSDYHA---IIDSVLC----MGVRYLSD 754
            |     ...|.|....|:|..:|..|:       :.|..|..|   :.:..:|    .|.|...:
Mosquito   723 LRSLAKNFLCRAGYKPCIEEAQRAFKK-------WMDSPDPDAGNPVANQFICPVFKWGTREEWE 780

  Fly   755 QDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYLEGLMGENSTHMVLSEFEDLMYLLYI 819
            ...||:|:..:.               |......:||..|.|
Mosquito   781 FGLQRVINFPES---------------RVKSERTYLLKTLAG----------------------- 807

  Fly   820 YKSNLASRPVIWQYIER--NYKVLCRAPNFLEH-----FKQLAGFVPRHQ------RSHFERL-- 869
                ..|:|.   .|:|  |..||....||.::     ||.|:|....:.      :::::.:
Mosquito   808 ----CPSQPF---KIDRLLNIMVLEDNGNFTDNDISLIFKMLSGGSSGYSTLFNFLKNNWDAIKL 865

  Fly   870 ----RQTIANHMMQE--GLNTNQTLIEVDSPL-------VGKKMKITENFQDKFEQQIHKWLLNE 921
                |:::.::|:..  ||.|.|...::.|.|       .|....|.|......:::. ||....
Mosquito   866 RFKDRESLWDNMINSATGLFTTQEGYDMVSQLYVQHQGEFGTAEHIIEKSLKNIKEET-KWSDEN 929

  Fly   922 LPQATSRSDALLSASLSAANG 942
            ||......|..|     |:||
Mosquito   930 LPVIEQWLDHFL-----ASNG 945

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	117/508 (23%)
		ERAP1_C	569..841	CDD:463368	56/287 (20%)
LOC1272139	XP_311017.5	None