Protein Alignment CG5849 and LOC1270378

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: XP_309093.5
• Gene: LOC1270378 / 1270378
• VectorBaseID: AGAMI1_011814
• Length: 1133
• Species: Anopheles gambiae
• Alignment Length: 896
• Identity: 189/896 - (21%)
• Similarity: 329/896 - (36%)
• Gaps: 222/896 - (24%)

  Fly    31 LPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDIQITVHRLMAE--- 92
            |||...|..|.|.|..::  ..|...|..:|::.:.:.||.:||||:   |:.||...|:..
Mosquito   126 LPNNVKPNRYILTIHPNL--TTLDVKGQVSIELYVEKETNFVVLHAQ---DLNITEKALVGPKGF 185

  Fly    93 GSEIVDDLTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASRPAGLYYMDYRDEENNH 157
            ..:|:..|.:|  |...|.    ||..:...:...|.|.|.:.:.|        .:|..:.:.:.
Mosquito   186 ALKILRMLEYT--PRQQLY----IETREKLRKKANYTLSIRWHSKM--------ILDQFEGDFDM 236

  Fly   158 TVYVAATQCEPTYGRLIFPCYDEPGFKSNFSIKITHGSSHSAISNMPVKEV------LAHGDLKT 216
            ...:|||..:|...|..|||:|||..::.|.|.:.....|..:||..|::.      :..|.|:
Mosquito   237 KKTLAATVLKPGSTRKAFPCFDEPHLRAAFKISLFRDRFHIGLSNSIVQDTDDVGFYMGTGLLR- 300

  Fly   217 TSFHTTPPISTYLVAFVISDF-------------------------------------------G 238
            ..|..|||:....|::|||||                                           .
Mosquito   301 DDFAETPPLPPDSVSWVISDFRRELLEPSAKYQKVNASGNGASAAGAGKVPPSTAGAGNGKSTPS 365

  Fly   239 SISET----YRGITQSIY---------TSPT---------------------SKEKGQV-----A 264
            .:::|    :|.:|..:.         |:||                     :|..|.|     |
Mosquito   366 KVTKTEKKPFRNLTAVLLSKNLFKLTNTAPTKEPTQIENDVTISAAESGPAVAKSNGTVLPEHDA 430

  Fly   265 LKNA----VRTVAA--------------------------LEDYFGVSYPLPKLDHVALKKNYGA 299
            |.|.    :||..|                          |:.:..|:|||.|||.|||......
Mosquito   431 LWNGDTALIRTAPAYSFYAPETHIAKGTFILHTSRDILEYLQQWLSVAYPLSKLDFVALPSLLDD 495

  Fly   300 AMENWGLITYKDVNLLKNISSDGQKRKLDLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFS 364
            ...:.|:|..:...|.:..:...::..:.::..:..|..|:||.|:||:.|.:.|:.||...|.|
Mosquito   496 LSSSLGIIVCRTSFLNEPTAISSKEYHMSVVKISEGIVKQYFGGLISPKVWKHKWLWEGLIRYLS 560

  Fly   365 YVITDLIYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKM 429
            ..:...|.|...|.::|:......|...::......:|   .|..| .|..|.....:.|.::.|
Mosquito   561 RFLLATIQPLWPMKELFLIDTLTKALDIDALQGWESIS---AGASD-SGDNDPFYVDKSAALLSM 621

  Fly   430 FHHAFRQKLFVRGISHFLEKYRYSVANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSE 494
            ...|..::.|.:.:..||:.|::..|...:|:.....::.:.:|         :||:|..||::.
Mosquito   622 LQSAIGERNFRQCLGKFLKTYQFQTAEPSDLWAICAKQVNNSKY---------VREMMNQWTNTA 677

  Fly   495 WLPILVVTRNYENNTITFT--------------QRSVHMKDE----------------------- 522
            ..|:|.||.|..:.|:..|              ...:..:.|
Mosquito   678 AFPLLNVTMNGTSLTVRQTGFRPAEYLAIYDEPMEEIEREGEQGRSTTTTPAPVDATGKSGSGEA 742

  Fly   523 --LWWIPINFATTQSPNFEDTQVDMFMPPQPQYTVSLEDLNIHVS---GRDWIMVNKQHTGFYLV 582
              .|..||:: .|...|..:|..:.....|....:.|....:.::   ...||.:|...||:|.|
Mosquito   743 GTRWVFPIHY-ITDVLNTNETAAEAEHKEQQSLIIWLNSSEVIITLNHTAQWIKLNHGQTGYYRV 806

  Fly   583 RYDTDNLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNEIEQVEVVFELLKYLELEED----V 643
            .||..|...:..|:|.|::|....:|:||..|:..|. |..:.......||:.|...|::    |
Mosquito   807 LYDEANWAKLVEQMQINNAVFSTQDRVGLVSDIFTLC-HANLIPCHAAMELISYFPKEKEWGPIV 870

  Fly   644 L------TWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGPTFRRV-YVEQGVNLAEDGMFRGI 701
            |      .|.::....||..          :..|:||:.:..:.:.: :.:.|.:  |..:.|.:
Mosquito   871 LGTSHLEKWRKILKYSECYL----------VLAEYVRQNLAKSIQVLGWDDTGED--ETKLLRPV 923

  Fly   702 LEIACSA-DLPECLEYTRRLAKEHIIDKIYFKDGSDYHAIIDSVLCMGVRY 751
            |.::.:. :..|.:::.:.|........|.........|.|.|||....:|
Mosquito   924 LMLSAALWEESETIKFAKGLVTNFTTHSIPIPPNLRSVAYIGSVLSGEFQY 974

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	123/574 (21%)
		ERAP1_C	569..841	CDD:463368	45/195 (23%)
LOC1270378	XP_309093.5	None