Protein Alignment CG5849 and LOC11176075

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: XP_061503385.1
• Gene: LOC11176075 / 11176075
• VectorBaseID: AGAMI1_012706
• Length: 1065
• Species: Anopheles gambiae
• Alignment Length: 975
• Identity: 254/975 - (26%)
• Similarity: 435/975 - (44%)
• Gaps: 128/975 - (13%)

  Fly    18 VSGSMGERERSLRLPNATYPLFYQLHISSDIHKGQLLFSGNATIDVAIRQSTNEIVLHAKNLTDI 82
            |:.|:.|   .||||.:..|:.|.:.:...:.:....|.|...:.|.:.:..:.:.||...|...
Mosquito   149 VASSVRE---DLRLPRSIEPVAYDIRLIPWLVEDNFTFLGTVEVLVNVLEDCSNVTLHVAALNIH 210

  Fly    83 QITVHR-----------------------LMAEGSEIVDDLTHTLHPTAALLIIHPIENYQAFEE 124
            ..:|.|                       |:.|..||..:||........|::..|:      ..
Mosquito   211 SASVERSTGRGEEQHSEAATADESSEGAPLVREMVEIDHNLTVASKQFYVLMLKTPL------RR 269

  Fly   125 GQQYRLEILYTAIMASRPAGLYYMDYRDEENNHTVYVAATQCEPTYGRLIFPCYDEPGFKSNFSI 189
            |:||.:.:.|..::.....|.|...|  ..||.|.::|.||.:||..|..|||:|||..|:.|:|
Mosquito   270 GEQYVVRLRYDGVLNDYLQGFYRSSY--TANNETRWIATTQFQPTDARRAFPCFDEPALKARFNI 332

  Fly   190 KITHGSSHSAISNMP------VKEVLAHG---DLKTTSFHTTPPISTYLVAFVISDFGSISETYR 245
            .|.......::||||      ..|....|   |:    :..:.|:||||||||:.|       |.
Mosquito   333 SIARTRDMISLSNMPRLRSYEASEPELQGYVWDV----YQQSVPMSTYLVAFVVCD-------YL 386

  Fly   246 GITQ---SIYTSPTSKEKGQVALKNAVRTVAALEDYFGVSYPLPKLDHVALKKNYGAAMENWGLI 307
            .:|.   :::....:....:.||....:.:..|||:|.:.|||||:|.:||......||||||||
Mosquito   387 NLTSGNFAVWARADAIGSARYALSVGPKLLKFLEDFFHIEYPLPKVDMIALPDFSAGAMENWGLI 451

  Fly   308 TYKDVNLL--KNISSDGQKRKLDLITQNHEIAHQWFGNLVSPEWWTYTWMNEGFATYFSYVITDL 370
            ||::..:|  :|:|:...|:.:..:.. ||:|||||||||:|.|||..|:|||||:|..|:..|.
Mosquito   452 TYRETAMLYEENVSAISNKQHVITVVA-HELAHQWFGNLVTPSWWTDLWLNEGFASYMEYLGVDA 515

  Fly   371 IYPNDKMMDMFMTHEADSAYSYNSFFDVHPMSHYVEGEKDIMGVFDIISYKRGACVIKMFHHAFR 435
            :.|..|.|:.|:.:|..:.:|.::....|.:|..|...::|..:||.|||.:||.:|:|..|...
Mosquito   516 VEPAWKSMEQFVVNELHNVFSLDALSSSHQISVEVHNPEEIHEIFDKISYGKGATIIRMMDHFLT 580

  Fly   436 QKLFVRGISHFLEKYRYSVANELNLFDALHSELQDDEYFSHQPWASRIREIMLSWTHSEWLPILV 500
            .::|.||::::|...:|..|::.:|::.|.:|.:....|...   :.::|||.:||.....|::.
Mosquito   581 TEVFKRGLTNYLNDKKYQSASQDDLWEYLTNEARRGGIFDDH---TSVKEIMDTWTLQTGFPVVF 642

  Fly   501 VTRNYENNTITFTQR--------------SVHMKDELWWIPINFATTQSPNFEDTQVDMFMPPQP 551
            |.|:||:::|.|.|.              :.|.:..||||||.:.|....||:.|:..::|..:.
Mosquito   643 VQRDYESDSIEFRQERFSFANALNGTDGVARHSERFLWWIPITYTTLGDSNFQQTKPSIWMKAEE 707

  Fly   552 QYTVSLEDLNIHVSGRDWIMVNKQHTGFYLVRYDTDNLMAIARQLQ--TNHSVIHPINRLGLFRD 614
            ...::..|:..|    ||::||.|.||:|.|.||..|...|.|.||  ..:..|...||..|..|
Mosquito   708 ALVINNHDIPSH----DWMIVNVQQTGYYRVNYDERNWQMIVRHLQDRNKYKTIAASNRAQLIDD 768

  Fly   615 LGPLIEHNEIEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSLFNEFVRRLVGP 679
            ...|.....:: ..|...:.:||..|.|.:.|......:..:......|.:..||.::...|:..
Mosquito   769 ALNLARAGYLD-YGVALNVTRYLVHETDYVPWKAAIAALNYIDSMFIRTRNYGLFKKYSMDLLEN 832

  Fly   680 TFRRVYVEQGVNLAEDGMFR--GILEIACSADLPECLEYTRRLAKEHIIDKIY---FKDGSDYHA 739
            .:|.|..|...:.....:::  .:|:..|.....:|:        .|.:.|.|   .:...|.:.
Mosquito   833 IYREVGFEDHRDSPLLTVYKRISVLKAVCHLGNKDCV--------NHCLRKYYEWMHQPNPDINN 889

  Fly   740 II-----DSVLCMGVRYLSDQDFQRIIDMMQEIDRASVYYDDIIYALRCTQSHRHLLYYLEGLMG 799
            .|     .:|.|..::|..:.::....:..|:...|| ..:.::.|:.|::....|..|||..|.
Mosquito   890 PISPNLKSTVYCTAIKYGDETEWDFAWERFQKATVAS-EKEILLSAMGCSRVPWILARYLENAMS 953

  Fly   800 ENSTHMVLSEF----EDLMYLLYIYKSNLASRPVIWQYIERNY-KVLCRAPNFLEHFKQLAGFVP 859
            :        |:    :|...:......|:..:|:.:.|:..|: |:.......:.:...:..:..
Mosquito   954 D--------EYGIRKQDAFRVFISVADNVIGQPIAFDYMRNNWAKMKSYFGASMSNLNIILKYCT 1010

  Fly   860 R--HQRSHFERLRQTIANHMMQEGLNTNQTLIEVDSPLVGKKMKITENFQDKFEQQIHKWLLNEL 922
            :  :..|....|::....|:...|....|.:...:|.:.         :.::..|.|..| |||:
Mosquito  1011 KRFNTESELLELKEFAEIHLKDSGRTIQQAIEWTESNIA---------WLNRNAQPIVNW-LNEV 1065

  Fly   923  922
            Mosquito  1066  1065

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	148/490 (30%)
		ERAP1_C	569..841	CDD:463368	62/288 (22%)
LOC11176075	XP_061503385.1	None