Protein Alignment CG5849 and Rnpepl1

DIOPT Version :10

• Sequence 1: NP_650979.1
• Gene: CG5849 / 42556
• FlyBaseID: FBgn0038897
• Length: 968
• Species: Drosophila melanogaster
• Sequence 2: NP_852070.3
• Gene: Rnpepl1 / 108657
• MGIID: 1914170
• Length: 720
• Species: Mus musculus
• Alignment Length: 630
• Identity: 151/630 - (23%)
• Similarity: 239/630 - (37%)
• Gaps: 162/630 - (25%)

  Fly   100 LTHTLHPTAALLIIHPIENYQAFEEGQQYRLEILYTAIMASRPAGLYYMDYRDEENNHTVYVAAT 164
            ||.||.|        .::.:|.|:      :.:.||:..|  || ::::|......|...:| .|
Mouse   144 LTVTLPP--------EVQAHQPFQ------VILRYTSTDA--PA-IWWLDPELTYGNAKPFV-FT 190

  Fly   165 QCEPTYGRLIFPCYDEPGFKSNFS--IKITHGSS--HSAISNMPVKEV-LAHGDLKTTSFHTTPP 224
            |......|..|||:|.|..|..:|  :|...|..  .||..::.|:|. |.|       ||...|
Mouse   191 QGHSVCNRSFFPCFDTPAVKCTYSAVVKAPLGVQVLMSATQSVYVEEEGLYH-------FHMEHP 248

  Fly   225 ISTYLVAFVISDFGSISETYRGITQSIYTSP------TSKEKGQVALKNAVRTVAALEDYFGVSY 283
            :..||||.|.   |.:.....|....::..|      |||..|.|.     :.::|.|..:| .|
Mouse   249 VPAYLVALVA---GDLKPADIGPRSRVWAEPCLLPTATSKLSGAVE-----QWLSAAERLYG-PY 304

  Fly   284 PLPKLDHVALKKNYG-AAMENWGLITYKDVNLLKNISSDGQKRKLDLITQNHEIAHQWFGNLVSP 347
            ...:.|.|.|..::. .|||| ..:|:    ::.:|....:...:|:|   ||:||.||||.|:.
Mouse   305 MWGRYDIVFLPPSFPIVAMEN-PCLTF----IISSILESDEFLVIDVI---HEVAHSWFGNAVTN 361

  Fly   348 EWWTYTWMNEGFATYFSYVITDLIY--------------PNDKMMDMFMTHEADSAYSYNSFFDV 398
            ..|...|::||.|||....||...|              ...:.|.:.......|.........|
Mouse   362 ATWEEMWLSEGLATYAQRRITTETYGAAFTCLETAFRLDALHRQMRLLGEDSPVSKLQVKLEPGV 426

  Fly   399 HPMSHYVEGEKDIMGVFDIISYKRGACVI----KMFHHAFRQKLFVRGISHFLEKYRYSVANELN 459
            :| ||       :|.:|   :|::|.|.:    ::.....|...|:|.   ::|||:::.....:
Mouse   427 NP-SH-------LMNLF---TYEKGYCFVYYLSQLCGGPQRFDDFLRA---YVEKYKFTSVVAQD 477

  Fly   460 LFDALHS---ELQDDEYFSHQPWASRIREIMLSWTHSEWL----PILVVTRNYENNTITFTQRSV 517
            |.|:..|   ||::...           :.........||    |.|......:.:::|   |.|
Mouse   478 LLDSFLSFFPELKEQSV-----------DCRAGLEFERWLNATGPPLAEPDLSQGSSLT---RPV 528

  Fly   518 HMKDELWWI-PINFA-------------TTQSPNFEDTQVDMFMPPQPQ---------YTVSLED 559
            ....:||.. |:..|             |.|:..|.|..:|  ..|.||         |:..|:.
Mouse   529 EALFQLWTAEPLEQAAASASAIDISKWRTFQTALFLDRLLD--GSPLPQEVVMSLSKCYSSLLDS 591

  Fly   560 LNIHVSGRDWIMVNKQHTGFYLVRYD-TDNLMAIARQLQTNHSVIHPINRLGLFRDLGPLIEHNE 623
            :|..:..| |:.:        :||.| ..:|..:.|.|::..|.::.|          ||.|
Mouse   592 MNAEIRIR-WLQI--------VVRNDYYPDLHRVRRFLESQMSRMYTI----------PLYE--- 634

  Fly   624 IEQVEVVFELLKYLELEEDVLTWNQLQDTIECLTRNLHGTSSQSL 668
                ::....||...||....|..:|...   |.|.:....||.|
Mouse   635 ----DLCTGALKSFALEVFYQTQGRLHPN---LRRTIQQILSQGL 672

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG5849	NP_650979.1	M1_APN-Q_like	38..492	CDD:341064	105/424 (25%)
		ERAP1_C	569..841	CDD:463368	23/101 (23%)
Rnpepl1	NP_852070.3	M1_LTA4H	29..507	CDD:341062	106/429 (25%)
		Leuk-A4-hydro_C	555..668	CDD:462686	32/143 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	671..708		1/2 (50%)