Protein Alignment E2f1 and E2f2

DIOPT Version :9

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: XP_003750109.1
• Gene: E2f2 / 684111
• RGDID: 1593939
• Length: 442
• Species: Rattus norvegicus
• Alignment Length: 311
• Identity: 108/311 - (34%)
• Similarity: 155/311 - (49%)
• Gaps: 62/311 - (19%)

  Fly   206 RHDADAELDEDVVERVAKPASHHPFSLSTPQQQL-----AASVASSSSSGDRNRADTSLGILTKK 265
            |..|..:||.:.:.|...|      ...||:.:.     ..|..:..|.|::.|.|||||:||||
  Rat    84 RLPAKRKLDLEGLGRPTVP------EFRTPKGKCIRVDGLPSPKTPKSPGEKTRYDTSLGLLTKK 142

  Fly   266 FVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMV------ 324
            |:.||.||.|||:|||.|:..|.||||||||||||||||.::.||||||||| .|:.:.
  Rat   143 FIYLLSESEDGVLDLNWAAEVLDVQKRRIYDITNVLEGIQLIRKKSKNNIQW-VGRGIFEDPTRP 206

  Fly   325 --SQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSG-GMAYVTQNDLLNVDLFKD 386
              .|:..:.:: :.:..||..::|.::..|..::|.|     :|:. .:||||..|:..|..||:
  Rat   207 AKEQQLGQELK-ELMNAEQTLDQLIQSCTLSFKHLTE-----DNANKKLAYVTYQDIRAVGNFKE 265

  Fly   387 QIVIVIKAPPEAKLVRSATALKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFLC--------- 442
            |.||.:||||:.:|.....|.:        ||       :||:|: ..|.|.|:||
  Rat   266 QTVIAVKAPPQTRLEVPDRAEE--------NL-------QIYLKS-TQGPIEVYLCPEEGQEADS 314

  Fly   443 --HDTSPENSPIAPGAGYVGAPG----AGCVRTATSTRLHPLTNQRLNDPL 487
              .:..|..|.::| ......||    :|...|..|:.|.|   |.:..||
  Rat   315 PTKEALPSTSTLSP-VPDCAQPGCSTDSGLAETIESSVLMP---QPVPPPL 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:280479	46/61 (75%)
		E2F_DD	327..444	CDD:304549	34/128 (27%)
		coiled coil	327..362	CDD:271137	6/34 (18%)
E2f2	XP_003750109.1	E2F_TDP	133..196	CDD:280479	47/63 (75%)
		E2F_DD	207..308	CDD:271137	35/122 (29%)
		coiled coil	207..242	CDD:271137	6/35 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351854
Domainoid	1	1.000	101	1.000	Domainoid score	I6766
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4037
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000356
OrthoInspector	1	1.000	-	-		otm46224
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12081
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X977
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	9	8.990