Protein Alignment E2f1 and E2f3

DIOPT Version :9

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: NP_001131098.2
• Gene: E2f3 / 291105
• RGDID: 1561600
• Length: 458
• Species: Rattus norvegicus
• Alignment Length: 299
• Identity: 103/299 - (34%)
• Similarity: 162/299 - (54%)
• Gaps: 52/299 - (17%)

  Fly   226 SHHPF---SLSTPQQQLAASVAS------SSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLN 281
            |.|.:   .|.||:.:..|::.|      ..|..::.|.|||||:|||||:.||.:|||||:|||
  Rat   134 SGHQYLSDGLKTPKGKGRAALRSPDSPKTPKSPSEKTRYDTSLGLLTKKFIQLLSQSPDGVLDLN 198

  Fly   282 EASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWR-CGQS----MVSQERSRHIEADSLRLEQ 341
            :|:..|.||||||||||||||||::::||||||:||. |..|    |::|  .:.:..:...|.|
  Rat   199 KAAEVLKVQKRRIYDITNVLEGIHLIKKKSKNNVQWMGCSLSEDGGMLAQ--CQGLSKEVTELSQ 261

  Fly   342 QENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVRSATA 406
            :|.:|::.|.....:|..::::.||. .:||||..|:..:...|||.|||:|||||.:
  Rat   262 EEKKLDELIQSCTLDLKLLTEDSENQ-RLAYVTYQDIRKISGLKDQTVIVVKAPPETR------- 318

  Fly   407 LKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPI------------APGAGYV 459
                     |.:|::....:|:: |...|.|.|:||.:.:..:.|:            .|.:..:
  Rat   319 ---------LEVPDSIESLQIHL-ASTQGPIEVYLCPEETETHRPMKTNNQDHNGNIPKPTSKDL 373

  Fly   460 GAPGAGCVRTATST-RLHPLTN-----QRLNDPLFNNID 492
            .:..:|....:.|| .|.||.:     |:..|.:.:|::
  Rat   374 ASNNSGHSDCSVSTANLSPLASPANLLQQTEDQIPSNLE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:280479	45/61 (74%)
		E2F_DD	327..444	CDD:304549	33/116 (28%)
		coiled coil	327..362	CDD:271137	6/34 (18%)
E2f3	NP_001131098.2	E2F_TDP	173..236	CDD:396755	46/62 (74%)
		E2F_DD	247..347	CDD:271137	34/119 (29%)
		coiled coil	247..282	CDD:271137	7/36 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	101	1.000	Domainoid score	I6766
eggNOG	1	0.900	-	-		E1_KOG2577
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	170	1.000	Inparanoid score	I4037
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000356
OrthoInspector	1	1.000	-	-		otm46224
orthoMCL	1	0.900	-	-		OOG6_101186
Panther	1	1.100	-	-	O	PTHR12081
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X977
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.860