| Sequence 1: | NP_001262809.1 | Gene: | E2f1 / 42550 | FlyBaseID: | FBgn0011766 | Length: | 821 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_808401.1 | Gene: | E2f2 / 242705 | MGIID: | 1096341 | Length: | 443 | Species: | Mus musculus |
| Alignment Length: | 280 | Identity: | 101/280 - (36%) |
|---|---|---|---|
| Similarity: | 141/280 - (50%) | Gaps: | 36/280 - (12%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 206 RHDADAELDEDVVERVAKPASHHPFSLSTPQQQL-----AASVASSSSSGDRNRADTSLGILTKK 265
Fly 266 FVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMVSQ---- 326
Fly 327 ERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIV 391
Fly 392 IKAPPEAKLVRSATALKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFLCHDTSPE-NSPIAPG 455
Fly 456 AGYVGA--PGAGCVRTATST 473 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| E2f1 | NP_001262809.1 | E2F_TDP | 256..318 | CDD:280479 | 46/61 (75%) |
| E2F_DD | 327..444 | CDD:304549 | 33/116 (28%) | ||
| coiled coil | 327..362 | CDD:271137 | 5/34 (15%) | ||
| E2f2 | NP_808401.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..22 | ||
| Cyclin A/CDK2 binding. /evidence=ECO:0000255 | 67..107 | 6/28 (21%) | |||
| E2F_TDP | 133..196 | CDD:280479 | 47/63 (75%) | ||
| Leucine-zipper | 157..178 | 15/20 (75%) | |||
| DEF box | 162..198 | 27/36 (75%) | |||
| Dimerization. /evidence=ECO:0000255 | 199..291 | 25/107 (23%) | |||
| E2F_DD | 207..308 | CDD:271137 | 33/117 (28%) | ||
| coiled coil | 207..242 | CDD:271137 | 5/34 (15%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 306..341 | 8/34 (24%) | |||
| Transactivation. /evidence=ECO:0000255 | 361..443 | ||||
| Retinoblastoma protein binding. /evidence=ECO:0000255 | 416..433 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167848246 | |
| Domainoid | 1 | 1.000 | 101 | 1.000 | Domainoid score | I6922 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2577 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000356 | |
| OrthoInspector | 1 | 1.000 | - | - | otm44132 | |
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 1 | 1.100 | - | - | O | PTHR12081 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X977 | |
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 1 | 0.960 | - | - | ||
| 11 | 10.800 | |||||