| Sequence 1: | NP_001262809.1 | Gene: | E2f1 / 42550 | FlyBaseID: | FBgn0011766 | Length: | 821 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001940.1 | Gene: | E2F3 / 1871 | HGNCID: | 3115 | Length: | 465 | Species: | Homo sapiens |
| Alignment Length: | 509 | Identity: | 147/509 - (28%) |
|---|---|---|---|
| Similarity: | 219/509 - (43%) | Gaps: | 110/509 - (21%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 106 SLDKG---HNTGAVATAAAAATAGHTQQQLQQQHHHQNQQQRKATGKSNDITNYYKVKRRPHAV- 166
Fly 167 SDEIHPKKQ-AKQSAHHQTVYQKHTASSAPQQLRHSHHQLRHDADAELDEDVVERVAKPASHHPF 230
Fly 231 ---SLSTPQQQLAASVAS------SSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNR 286
Fly 287 LHVQKRRIYDITNVLEGINILEKKSKNNIQWR-CGQS----MVSQERSRHIEADSLRLEQQENEL 346
Fly 347 NKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVRSATALKFQP 411
Fly 412 LPFNLNLPNTKLPREIYVKAENSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLH 476
Fly 477 PLTNQRLNDPLFNNIDAMSTKGLFQTPYRSARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQ 541
Fly 542 QQQQQQQQLLQQPEEDDVDVELNQLVPTLTNPVVR-THQFQQHQQPSIQELFSS 594 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| E2f1 | NP_001262809.1 | E2F_TDP | 256..318 | CDD:280479 | 45/61 (74%) |
| E2F_DD | 327..444 | CDD:304549 | 33/116 (28%) | ||
| coiled coil | 327..362 | CDD:271137 | 6/34 (18%) | ||
| E2F3 | NP_001940.1 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 96..179 | 14/82 (17%) | |
| Cyclin A/CDK2 binding. /evidence=ECO:0000255 | 101..153 | 9/51 (18%) | |||
| E2F_TDP | 180..243 | CDD:280479 | 46/62 (74%) | ||
| Leucine-zipper | 204..225 | 15/20 (75%) | |||
| DEF box | 209..245 | 25/35 (71%) | |||
| Dimerization. /evidence=ECO:0000255 | 246..337 | 29/109 (27%) | |||
| E2F_DD | 254..354 | CDD:271137 | 34/119 (29%) | ||
| coiled coil | 254..289 | CDD:271137 | 7/36 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 357..389 | 12/79 (15%) | |||
| Transactivation. /evidence=ECO:0000255 | 391..465 | 15/66 (23%) | |||
| Retinoblastoma protein binding. /evidence=ECO:0000255 | 432..449 | 2/16 (13%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 1 | 1.000 | 101 | 1.000 | Domainoid score | I6928 |
| eggNOG | 1 | 0.900 | - | - | E1_KOG2577 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 1 | 1.000 | - | - | FOG0000356 | |
| OrthoInspector | 1 | 1.000 | - | - | otm42079 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101186 | |
| Panther | 1 | 1.100 | - | - | O | PTHR12081 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X977 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 1 | 0.960 | - | - | ||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 10 | 9.770 | |||||