Protein Alignment E2f1 and efl-1

DIOPT Version :9

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: NP_507289.1
• Gene: efl-1 / 180133
• WormBaseID: WBGene00001161
• Length: 342
• Species: Caenorhabditis elegans
• Alignment Length: 193
• Identity: 64/193 - (33%)
• Similarity: 103/193 - (53%)
• Gaps: 44/193 - (22%)

  Fly   203 HQLRHDADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDRNRADTSLGILTKKFV 267
            ::|..|.|.:.|||               |..||.              ..|||.|||:|.|:|:
 Worm    43 NELDFDFDFDEDED---------------LDQPQM--------------GTRADKSLGLLAKRFI 78

  Fly   268 DLLQESPDGVVDLNEASNRLHV-QKRRIYDITNVLEGINILEKKSKNNIQWRCGQSMVS------ 325
            .::|.||.|..|||.|:..|:| |||||||||||||||.::||:|||.|||:.|..|::
 Worm    79 RMIQYSPYGRCDLNTAAEALNVRQKRRIYDITNVLEGIGLIEKRSKNMIQWKGGDFMLNVKEGKR 143

  Fly   326 -------QERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLNV 381
                   ::|...::|:..:|.::|..:.:....::::|..:::.|||: .::||.::.|..:
 Worm   144 QSATTEEEDRMEQLKAEIEQLNKEEELIEQRQRWLQQSLRNMTESVENN-KLSYVLRSQLAEI 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:280479	39/62 (63%)
		E2F_DD	327..444	CDD:304549	11/55 (20%)
		coiled coil	327..362	CDD:271137	5/34 (15%)
efl-1	NP_507289.1	E2F_TDP	67..131	CDD:367033	40/63 (63%)
		coiled coil	152..187	CDD:271137	5/34 (15%)
		E2F_CC-MB	157..254	CDD:374536	10/50 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	81	1.000	Domainoid score	I5541
eggNOG	1	0.900	-	-		E1_KOG2577
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000356
OrthoInspector	1	1.000	-	-		oto19305
orthoMCL	1	0.900	-	-		OOG6_101186
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3254
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.740