Protein Alignment E2f1 and efl-2

DIOPT Version :9

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: NP_001122660.1
• Gene: efl-2 / 174980
• WormBaseID: WBGene00001162
• Length: 358
• Species: Caenorhabditis elegans
• Alignment Length: 421
• Identity: 107/421 - (25%)
• Similarity: 165/421 - (39%)
• Gaps: 127/421 - (30%)

  Fly   233 STPQQQLAASVASSSSSGDRNRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDI 297
            |..||....:.|::.|..:..|:..|||::|::|:.|.|.:.  |::|||.:..|::.|||:||:
 Worm    15 SEQQQHEDGAAAAAGSPKEVFRSQQSLGLITQRFMSLRQRNE--VLNLNEVAKELNISKRRVYDV 77

  Fly   298 TNVLEGINILEKKSKNNIQWRCGQSMVSQERSRHIEADSLRLEQQENELNKAIDLM-RENLAEIS 361
            .|||||:..:||..||||:| .|.:..|:|::. :||....|.|||    |.::|| |:..|.|.
 Worm    78 INVLEGLGYVEKVEKNNIRW-IGDNNNSEEQNA-LEARVEMLRQQE----KLLELMIRDAQAIIE 136

  Fly   362 QEVEN--SGGMAYVTQNDLLNVDLFKDQIVIVIKAPPEAKLVRSATALKFQPLPFNLNLPNTKLP 424
            ...|:  .....||::.|              |:...|                     ||||
 Worm   137 LHFEDPIERPYNYVSKED--------------IRKTAE---------------------PNTK-- 164

  Fly   425 REIYVKAE----NSGEINVFLCHDTSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLND 485
             .|.||:|    :|.||.|     |.|..|         |:... .||.....:.|.|.  ..||
 Worm   165 -SIIVKSELDTSSSFEIQV-----TDPSTS---------GSHDM-IVRNKNGVKSHALL--FTND 211

  Fly   486 PL-------FNNIDAMSTKGLFQTPYRSARNLSKSIEEAAK-QSQPEYNNICDIAMGQHHNLNQQ 542
            |.       .:::..:|::..|:|.......|::.:.:... .|.|::..
 Worm   212 PPEYGDEEDEDDVKKLSSQKRFETSEALRVTLAEMLTDPTTISSSPKHIK--------------- 261

  Fly   543 QQQQQQQLLQQPEE-DDVDVELNQLVPTLT-------------------NPVVRTHQFQQHQQPS 587
                    |::||| |..|:|...|.|:.:                   :|      |:....|.
 Worm   262 --------LEEPEEIDTEDLETFVLPPSTSASQSNAPYLPETPGRGLFFSP------FKSLIDPC 312

  Fly   588 IQELFSSLTESSPPTPTKRRREAAAAAIAAG 618
            |...||....|.....|...|...|.|.|:|
 Worm   313 ILPSFSDDLTSGYINITTPSRATGAGAGASG 343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:280479	28/61 (46%)
		E2F_DD	327..444	CDD:304549	31/123 (25%)
		coiled coil	327..362	CDD:271137	13/35 (37%)
efl-2	NP_001122660.1	E2F_TDP	37..99	CDD:367033	29/64 (45%)
		coiled coil	105..140	CDD:271137	13/39 (33%)
		E2F_DD	110..200	CDD:389902	36/146 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166498
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000356
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.840