Protein Alignment E2f1 and e2f1

DIOPT Version :10

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: XP_012808274.2
• Gene: e2f1 / 100493924
• XenbaseID: XB-GENE-481741
• Length: 428
• Species: Xenopus tropicalis
• Alignment Length: 640
• Identity: 142/640 - (22%)
• Similarity: 212/640 - (33%)
• Gaps: 288/640 - (45%)

  Fly   193 SAPQQLRHSHHQLRHD-----ADAELDEDVVERVAKPASHHPFSLSTPQQQLAASVASSSSSGDR 252
            :.||....|:...|.|     ...:||.:.|.|..:.|      |.||:.:....:.:..|.|:|
 Frog    59 TTPQGPSTSYTAQRPDLGRPPVKRKLDLETVSRYNQEA------LQTPRGKGKRPLKAVKSPGER 117

  Fly   253 NRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHVQKRRIYDITNVLEGINILEKKSKNNIQW 317
            :|.||||.:.||:|::||.:|.|||||||.|:..|:||||||||||||||||:::.|||||:|||
 Frog   118 SRYDTSLHLTTKRFLELLSQSSDGVVDLNWAAQVLNVQKRRIYDITNVLEGIHLITKKSKNHIQW 182

  Fly   318 RCGQSMVSQERSRHIEA--DSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQNDLLN 380
             .|.:..::..||:..|  |..:||.||.:|:|.|.:....|....:|..::.|  |||..||.:
 Frog   183 -LGYTSYAEYNSRYQSALKDCQKLEDQEKQLDKLIHMANTQLKLFKEEECHNFG--YVTCQDLRS 244

  Fly   381 VDLFKDQIVIVIKAPPEAKLVRSATALKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFLCHD- 444
            :....:::::||:.||:..:..|..|..||     ::|.:|:.|            |:||||.|
 Frog   245 IADPSERMLMVIRYPPDTDMCVSDPAEAFQ-----MSLKSTQAP------------IDVFLCPDD 292

  Fly   445 ----TSPENSPIAPGAGYVGAPGAGCVRTATSTRLHPLTNQRLNDPLFNNIDAMSTKGLFQTPYR 505
                .||..||                 |.||
 Frog   293 SSGVCSPVTSP-----------------TKTS--------------------------------- 307

  Fly   506 SARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQPEEDDVDVELNQLVPTL 570
                          |::|.                                     .:||..|.
 Frog   308 --------------QAEPS-------------------------------------SINQAEPL- 320

  Fly   571 TNPVVRTHQFQQHQQPSIQELFSSLTESSPPTPTKRRREAAAAAIAAGSSTTATTTLNSHNNRNH 635
                           ||:|.     .|.||
 Frog   321 ---------------PSVQP-----KEESP----------------------------------- 330

  Fly   636 SNHSNHSNHSSSNNSKSQPPTIGYGSSQRRSDVPMYNCAMEGATTTSATADTTAATSRSAAASSL 700
                                          :.:||.:
 Frog   331 ------------------------------ASIPMLD---------------------------- 337

  Fly   701 QMQFAAVAESNNGSSSGGGGGGGGYGSIAGAGANADPHQPYSHDRNSLPPGVADCDANSNSSSVT 765
                                        .|.|..:|..:|:....|.:|     .|:..|...::
 Frog   338 ----------------------------IGLGLLSDMQEPFLPPENEIP-----LDSTLNCLPLS 369

  Fly   766 LQGLDALFNDIGSDYFSNDIAFVSINPPDDNDYPYALNANEGIDRLFDFGSDAYG 820
            ...|...:.|...|:..||  |:|::|....:|.:.|...||...||:|..|..|
 Frog   370 PSNLLLDYRDAMPDFLPND--FISLSPASSQEYSFGLQTCEGAAELFNFDCDFSG 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:460530	42/61 (69%)
		E2F_DD	327..444	CDD:473951	35/118 (30%)
		coiled coil	327..362	CDD:271137	12/36 (33%)
e2f1	XP_012808274.2	E2F_TDP	120..184	CDD:460530	43/64 (67%)
		E2F_DD	193..292	CDD:271137	35/117 (30%)
		coiled coil	193..227	CDD:271137	12/33 (36%)