Protein Alignment E2f1 and e2f4

DIOPT Version :10

• Sequence 1: NP_001262809.1
• Gene: E2f1 / 42550
• FlyBaseID: FBgn0011766
• Length: 821
• Species: Drosophila melanogaster
• Sequence 2: NP_001107966.1
• Gene: e2f4 / 100038079
• XenbaseID: XB-GENE-482721
• Length: 374
• Species: Xenopus tropicalis
• Alignment Length: 372
• Identity: 115/372 - (30%)
• Similarity: 188/372 - (50%)
• Gaps: 58/372 - (15%)

  Fly   253 NRADTSLGILTKKFVDLLQESPDGVVDLNEASNRLHV-QKRRIYDITNVLEGINILEKKSKNNIQ 316
            :|.:.|||:||.|||.||||:.|||:||..|::.|.| |||||||||||||||.::||||||:||
 Frog    12 SRHEKSLGLLTSKFVSLLQEAEDGVLDLKAAADTLAVRQKRRIYDITNVLEGIGLIEKKSKNSIQ 76

  Fly   317 WR-----CGQSMVSQERSRHIEADSLRLEQQENELNKAIDLMRENLAEISQEVENSGGMAYVTQN 376
            |:     |....:: ::...::|:...|||:|.||::....:::::..::.:|:|: |:||:|..
 Frog    77 WKGVGPGCNTREIA-DKLIDLKAELADLEQREQELDQQRVWVQQSIKNVTDDVQNT-GLAYLTHE 139

  Fly   377 DLLNVDLFKDQIVIVIKAPPEAKLVRSATALKFQPLPFNLNLPNTKLPREIYVKAENSGEINVFL 441
            |:..  .|:...::.|:||       |.|.|:. |:|.|   .|.:...:|::|: .:|.|.|.|
 Frog   140 DICR--CFRGDTLLAIRAP-------SGTCLEV-PVPEN---TNGQKKFQIHLKS-TTGPIEVLL 190

  Fly   442 CH-DTS---PENSPIAPGAGYVGAPGAGCVRTATSTRLHP-LTNQRLNDPLFNNIDAMSTKGLFQ 501
            .: |||   |...|:.|....:.||.     |..||...| ||.|  ||...:.:.||....:..
 Frog   191 VNKDTSSSPPVVVPVPPPEDLIQAPA-----TVPSTPQRPALTPQ--NDTAASPVPAMPDSPISN 248

  Fly   502 TPYR------------SARNLSKSIEEAAKQSQPEYNNICDIAMGQHHNLNQQQQQQQQQLLQQP 554
            :..:            :|.:...||:....||....:|..|:.  ......|..:.....:|:.|
 Frog   249 SESQDCTTDQTLSMENTASSRLSSIDTCPLQSSASLDNSTDLP--DPSTSFQPIKSDLSDVLELP 311

  Fly   555 EEDDVDVELNQLVPTLTNPVVRTHQFQQHQQPSIQELFSSLTESSPP 601
            :  |:....:|....:|:.::        ::....|:|:.|...|||
 Frog   312 K--DISDLFDQTKECITSDLL--------EELMSSEVFAPLLRLSPP 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
E2f1	NP_001262809.1	E2F_TDP	256..318	CDD:460530	43/62 (69%)
		E2F_DD	327..444	CDD:473951	31/117 (26%)
		coiled coil	327..362	CDD:271137	7/34 (21%)
e2f4	NP_001107966.1	E2F_TDP	14..79	CDD:460530	44/64 (69%)
		E2F_DD	91..194	CDD:271137	31/117 (26%)
		coiled coil	91..126	CDD:271137	7/34 (21%)