| Sequence 1: | NP_524436.2 | Gene: | InR / 42549 | FlyBaseID: | FBgn0283499 | Length: | 2144 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001353483.1 | Gene: | ntrk2a / 65090 | ZFINID: | ZDB-GENE-010126-1 | Length: | 791 | Species: | Danio rerio |
| Alignment Length: | 468 | Identity: | 151/468 - (32%) |
|---|---|---|---|
| Similarity: | 218/468 - (46%) | Gaps: | 116/468 - (24%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 1274 LNEGLYSFRVRANSIAGYGDFTEV--EHIKVEP-------------------PPSYAKVFFWLLG 1317
Fly 1318 IGLAFLIVSLFGYVCYLHKRK--------------VPSND------LH-------------MNTE 1349
Fly 1350 V------------NP--FYASMQYIPDD---WEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNG 1397
Fly 1398 VDRE---CAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMELMKKGDL 1459
Fly 1460 KSYLRAHRPEERDEAMMTYLNRIGVTGNVQPP---TYGRIYQMAIEIADGMAYLAAKKFVHRDLA 1521
Fly 1522 ARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVL 1586
Fly 1587 WEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCW----HHR----------- 1636
Fly 1637 --SSARPSFLDII 1647 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| InR | NP_524436.2 | Recep_L_domain | 356..465 | CDD:460032 | |
| Furin-like | 510..645 | CDD:395614 | |||
| Recep_L_domain | 663..781 | CDD:460032 | |||
| FN3 | 791..>964 | CDD:442628 | |||
| FN3 | 1224..1302 | CDD:238020 | 6/29 (21%) | ||
| PTKc_InsR_like | 1364..1652 | CDD:173625 | 123/307 (40%) | ||
| ntrk2a | NP_001353483.1 | LRR_8 | 84..143 | CDD:404697 | |
| leucine-rich repeat | 86..109 | CDD:275378 | |||
| leucine-rich repeat | 110..132 | CDD:275378 | |||
| Ig | 186..272 | CDD:472250 | |||
| Ig strand B | 203..207 | CDD:409353 | |||
| Ig strand C | 216..220 | CDD:409353 | |||
| Ig strand E | 239..243 | CDD:409353 | |||
| Ig strand F | 254..259 | CDD:409353 | |||
| Ig strand G | 267..270 | CDD:409353 | |||
| Ig | 277..370 | CDD:472250 | 6/28 (21%) | ||
| Ig strand B | 292..296 | CDD:409353 | |||
| Ig strand C | 305..309 | CDD:409353 | |||
| Ig strand E | 335..339 | CDD:409353 | |||
| Ig strand F | 349..354 | CDD:409353 | 1/4 (25%) | ||
| Ig strand G | 362..365 | CDD:409353 | 0/2 (0%) | ||
| Protein Kinases, catalytic domain | 499..788 | CDD:473864 | 120/302 (40%) | ||
| Blue background indicates that the domain is not in the aligned region. | |||||