Protein Alignment InR and tor

DIOPT Version :9

• Sequence 1: NP_001138093.1
• Gene: InR / 42549
• FlyBaseID: FBgn0283499
• Length: 2144
• Species: Drosophila melanogaster
• Sequence 2: NP_476762.1
• Gene: tor / 35717
• FlyBaseID: FBgn0003733
• Length: 923
• Species: Drosophila melanogaster
• Alignment Length: 907
• Identity: 190/907 - (20%)
• Similarity: 327/907 - (36%)
• Gaps: 320/907 - (35%)

  Fly  1025 DDRKVQAGMEFENAL----QNFIFVPNIRKSKNGS----SDKSDGAEG--------AALDSNAIP 1073
            ||.|       |.||    .||:.:|.:..:...:    :...||:..        |.|.....|
  Fly   119 DDNK-------ETALYLSDDNFLILPGLESNSTHNITALAMHGDGSYSLIAKDQTFATLIRGYQP 176

  Fly  1074 NG-GATNPSRRRRDVALEPELDDVEGSVLLRHVRSITD-----DTDAFFE--------------- 1117
            :. ||.|..|      ..|:.||      |.|:.:..:     :::.:|:
  Fly   177 SKMGAVNLLR------FVPQPDD------LHHIAAEIEWKPSAESNCYFDMVSYSTNSVNMDEPL 229

  Fly  1118 ----KDDENTYKDEED-LSSNKQFYEVFAKELPPNQTHFVFEKLRHFTRY-AIFVVACREEIPSE 1176
                :|.:..|:...| |..:|| |.|..:      |..:..:|....:: .|.|.:|.:..|
  Fly   230 EVQFRDRKKLYRHTVDNLEFDKQ-YHVGVR------TVNIMNRLESDLQWLPIAVPSCLDWYP-- 285

  Fly  1177 KLRDTSFKKSLCSDYDTVFQTTKRKKFADIVMDLKVDLEHANNTESPVRVRWTPP--VDPNGEIV 1239
                  :..:||..:.....|..:|::...::.|              .:.|..|  :..|..:.
  Fly   286 ------YNYTLCPPHKPENLTVTQKQYLPNILAL--------------NITWARPRYLPDNYTLH 330

  Fly  1240 TY-------EVAYKLQKPDQVEEKKCIP-----AADFN-----QTAGYLIKLNEGLYSFRVRANS 1287
            .:       |:.|.|   ||......:|     .:.|.     |:||.  |...||...:|....
  Fly   331 IFDLFKGGTELNYTL---DQNRSHFYVPKITVLGSHFEVHLVAQSAGG--KNVSGLTLDKVHRGV 390

  Fly  1288 IAGYGDFTEVEHIKVEPPPSYAKVFFWLLGIGLAFLIVSLFGYVCYLHKRKVPSNDLHM---NTE 1349
            :...|:..::             |.|.::.|....::.||  ..|..::.:|.:  |.|   :.:
  Fly   391 LLSEGNMVKL-------------VLFIIVPICCILMLCSL--TFCRRNRSEVQA--LQMDAKDAK 438

  Fly  1350 VNPFYASMQ---------------YIPDDWEVLRENIIQLAPLGQGSFGMVYEGILKSFPPNGVD 1399
            .:.|:.|:.               .:.|:.||...:::....||:|:||:|..|:.|.
  Fly   439 ASEFHLSLMDSSGLLVTLSANESLEVMDELEVEPHSVLLQDVLGEGAFGLVRRGVYKK------- 496

  Fly  1400 RECAIKTVNENATDRERTNFLSEASVMKEFDTY-HVVRLLGVCSR-GQPALVVMELMKKGDLKSY 1462
            |:.|:|.:.:...|.:...|..|..::|....: ::|.::|..:| ....::::|....|.|:::
  Fly   497 RQVAVKLLKDEPNDEDVYAFKCEIQMLKAVGKHPNIVGIVGYSTRFSNQMMLLIEYCSLGSLQNF 561

  Fly  1463 LRAH-----------------------------------RPEERDEAMM---------------- 1476
            ||..                                   |.|:.:.:|:
  Fly   562 LREEWKFRQEQNAIGLKKNLEQNVDNRRFNRLPRNSIHDRIEDINNSMLSTVEEESESDQTHSSR 626

  Fly  1477 --TY-LNRI---------------GVTGNVQPPT------------------------------- 1492
              || |.||               .:.|:..|.|
  Fly   627 CETYTLTRITNAADNKGYGLEDIENIGGSYIPKTAEAPKDRPKRKLKPQPKKDSKQDFKSDNKKR 691

  Fly  1493 -----------------------YGRIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVK 1534
                                   |..:..:|.::|.||.:||..|.|||||||||.:::.|.::|
  Fly   692 IFENKEYFDCLDSSDTKPRIPLKYADLLDIAQQVAVGMEFLAQNKVVHRDLAARNVLISVDRSIK 756

  Fly  1535 IGDFGMTRDIYETDYYRK-GTKGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQ 1598
            |.|||::||:|..:.||| |..|.||::|:..|||...||:|.|||:||||:|:|:.||...||.
  Fly   757 IADFGLSRDVYHENVYRKSGGSGKLPIKWLALESLTHQVYTSQSDVWSFGVLLYEITTLGGMPYP 821

  Fly  1599 GLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVS 1663
            .:|...:|:.:..|..|:|||.|...:..||:.||....|.||:|
  Fly   822 SVSPSDLLQLLRQGHRMKRPEGCTQEMFSLMESCWSSVPSHRPTF-------------------- 866

  Fly  1664 FYHSEAGLQHREKERKERNQLDAFAAVPLDQDLQDREQQEDATTPLRMGDYQ-QNSSLDQPP 1724
                 :.|:||           ....:....|:.:|.:|..|.|..::.... .||.::|.|
  Fly   867 -----SALKHR-----------LGGMILATNDVPERLKQLQAATESKLKSCDGLNSKVEQVP 912

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
InR	NP_001138093.1	Recep_L_domain	356..465	CDD:279382
		Furin-like	512..645	CDD:279142
		FU	545..592	CDD:238021
		Recep_L_domain	663..781	CDD:279382
		FN3	1224..1302	CDD:238020	18/96 (19%)
		PTKc_InsR_like	1364..1652	CDD:173625	105/413 (25%)
		Pkinase_Tyr	1371..1650	CDD:285015	103/404 (25%)
tor	NP_476762.1	FN3	199..261	CDD:214495	10/68 (15%)
		STYKc	475..873	CDD:214568	106/440 (24%)
		PTKc	479..873	CDD:270623	106/436 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24416
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.010