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Protein Alignment InR and Ntrk3

DIOPT Version :10

Sequence 1:	NP_524436.2	Gene:	InR / 42549	FlyBaseID:	FBgn0283499	Length:	2144	Species:	Drosophila melanogaster
Sequence 2:	NP_001257585.1	Gene:	Ntrk3 / 29613	RGDID:	3214	Length:	864	Species:	Rattus norvegicus

Alignment Length:	581	Identity:	169/581 - (29%)
Similarity:	247/581 - (42%)	Gaps:	167/581 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly  1207 VMDLKVDLEHANNTESPVRVRWTPPVD--PNGEIVTYEVAYKLQKPDQVEE----KKCIPAADFN 1265
            :::.:|.|||.  .|..||...||.:.  .||:.:...   |:...|..:|    :.|:.   ||
  Rat   310 LVEPEVRLEHC--IEFVVRGNPTPTLHWLYNGQPLRES---KIIHMDYYQEGEVSEGCLL---FN 366

  Fly  1266 QTAGYLIKLNEGLYSFRVRANSIAGYGDFTEVEHIKVEPPPSYAKVFFW---------------- 1314
            :...|    |.|.|:  :.|.:..|..:.|...|...||.|.....|.:
  Rat   367 KPTHY----NNGNYT--LIAKNALGTANQTINGHFLKEPFPESTDFFDFESDASPTPPITVTHKP 425

  Fly  1315 -------LLGIGLA----FLIVSLF---------------GYVCYLHKRKVPSNDL-HMNTEVN- 1351
                   .:.:|||    .|:|.||               |.|..:...:..::.| |:|..:.
  Rat   426 EEDTFGVSIAVGLAAFACVLLVVLFIMINKYGRRSKFGMKGPVAVISGEEDSASPLHHINHGITT 490

  Fly  1352 ------------------PFYASMQYI--------PDDW--EVLRENIIQLAPLGQGSFGMVYEG 1388
                              |...:.||.        ||.:  .:.|.:|:....||:|:||.|:..
  Rat   491 PSSLDAGPDTVVIGMTRIPVIENPQYFRQGHNCHKPDTYVQHIKRRDIVLKRELGEGAFGKVFLA 555

  Fly  1389 ILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHVVRLLGVCSRGQPALVVMEL 1453
            ...:..|.......|:|.: ::.|...|.:|..||.::......|:|:..|||..|.|.::|.|.
  Rat   556 ECYNLSPTKDKMLVAVKAL-KDPTLAARKDFQREAELLTNLQHEHIVKFYGVCGDGDPLIMVFEY 619

  Fly  1454 MKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPT------YGRIYQMAIEIADGMAYLAA 1512
            ||.|||..:||||.|    :||      |.|.|  ||..      ..::..:|.:||.||.|||:
  Rat   620 MKHGDLNKFLRAHGP----DAM------ILVDG--QPRQAKGELGLSQMLHIASQIASGMVYLAS 672

  Fly  1513 KKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKG--TKG------------------- 1556
            :.|||||||.|||:|..:|.||||||||:||:|.|||||:|  .||
  Rat   673 QHFVHRDLATRNCLVGANLLVKIGDFGMSRDVYSTDYYREGPYQKGPFSVSWQQQRLAASAASTL 737

  Fly  1557 ------------------LLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNE 1603
                              :||:|||||||:....:::.|||:||||:|||:.|...||:..|||.
  Rat   738 FNPSGNDFCIWCEVGGHTMLPIRWMPPESIMYRKFTTESDVWSFGVILWEIFTYGKQPWFQLSNT 802

  Fly  1604 QVLRYVIDGGVMERPENCPDFLHKLMQRCW-----------------HHRSSARPSFLDII 1647
            :|:..:..|.|:|||..||..::.:|..||                 |....|.|.:|||:
  Rat   803 EVIECITQGRVLERPRVCPKEVYDVMLGCWQREPQQRLNIKEIYKILHALGKATPIYLDIL 863

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.