DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment slou and npm1b

DIOPT Version :9

Sequence 1:	NP_001262808.1	Gene:	slou / 42547	FlyBaseID:	FBgn0002941	Length:	698	Species:	Drosophila melanogaster
Sequence 2:	XP_005173145.2	Gene:	npm1b / 553507	ZFINID:	ZDB-GENE-080723-7	Length:	316	Species:	Danio rerio

Alignment Length:	235	Identity:	53/235 - (22%)
Similarity:	69/235 - (29%)	Gaps:	80/235 - (34%)

- Green bases have known domain annotations that are detailed below.

  Fly   350 DLSDYGFRIQLGGLAAAAAAAAATSR----QIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSV 410
            ||.|.....|| .|.:....|.|..:    ::...||....|...|.|            ..|||
Zfish    47 DLDDDEAEHQL-SLKSVCLGAEAEDKFHTVEMEGLTYDGKTTKITLAV------------LKPSV 98

  Fly   411 CPVDLTRSVNSSAAANPSS-----------------ASTSASSDRDAATKRLAFSVENILDPNKF 458
            .|   :.|:.......|.|                 .|...|.|.|...:      ||...|.|.
Zfish    99 LP---SLSLGGFEVTPPVSFRLQSGGGPVYISGQHFVSVKESDDEDEEEE------ENNTSPVKR 154

  Fly   459 TGN----KLPSGPFGHPRQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSS 519
            ..|    |:|                  |::|..|..||..:.|.:|.|.||  ||..:.||...
Zfish   155 PSNMTLAKVP------------------QKKLKMDSDEDEDSDDDDDDDDDD--DDDEEEDDDKQ 199

  Fly   520 E-------------TDSKKGGSRNGDGKSGGGGGGGSKPR 546
            |             |..||..:...:|......|...||:
Zfish   200 EKPAVKSPVKSTQKTPEKKKSADKQNGSPDKKAGTSGKPQ 239

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeobox	549..601	CDD:278475
npm1b	XP_005173145.2	Nucleoplasmin	32..131	CDD:308605	20/99 (20%)
npm1b	XP_005173145.2	NPM1-C	265..313	CDD:318505
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900