Protein Alignment slou and NKX1-1

DIOPT Version :9

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001277008.1
• Gene: NKX1-1 / 54729
• HGNCID: 24975
• Length: 448
• Species: Homo sapiens
• Alignment Length: 488
• Identity: 152/488 - (31%)
• Similarity: 182/488 - (37%)
• Gaps: 212/488 - (43%)

  Fly   341 SSSGSPSGRDLSDYGFRIQLG-GLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGS 404
            |:||..:..|:.......|.| |.|..|.||||                         :::.||.
Human     2 SASGPEAPGDIPALPPPPQPGSGPAPPAPAAAA-------------------------QEAMDGR 41

  Fly   405 HSTPSVCPVDLTRSVNSSAAANPSSASTS-------ASSDRDAATKR-LAFSVENILDPNKFTGN 461
            ...|:.          ..|.|.|.:||.:       |.:.|.||..| .:|||.:|||||||...
Human    42 AELPAF----------PRAGAPPLAASDTVPAAPEGAGAARPAAPLRPTSFSVLDILDPNKFNSR 96

  Fly   462 K-------------------LPSGP----FGHPRQWSYERDEEMQERL----------------- 486
            :                   .|..|    .|.|     .|.||::.|.
Human    97 RRRCVLLGPVAPAACAPCASAPCAPAPAASGRP-----PRAEELERRALAGAGGVGAAGAEPPNA 156

  Fly   487 -DDDQSEDMSAQDLNDMDQ------------DDMCDDGSDIDDPSSETDSKKG-----GSRNGDG 533
             |..::.:....|.|....            |::.||..|.:|.:.||::.:|     |...|.|
Human   157 GDPFKAGEAETNDTNGYSSGGGGHSPSADSGDEVPDDEDDDEDEAPETEAARGAEEARGGGGGLG 221

  Fly   534 KSGGG----------------------------------------GGGGS--------------- 543
            ..|.|                                        ||.|:
Human   222 ARGSGCQGAAETDASPGATVDEAAAPGPRENSPVAQGPPGGAAAPGGAGTTPQGTATAAKPKRKR 286

  Fly   544 --------KPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 600
                    |||||||||||||||:||||||.||||||||||||||||||||||||||||||||||
Human   287 TGSDSKSGKPRRARTAFTYEQLVALENKFKATRYLSVCERLNLALSLSLTETQVKIWFQNRRTKW 351

  Fly   601 KKQNPGMDVNSPTIPPPGGGSFGPGA-----YASGLLYSHAVPYPPYGPYFHPLGAHHLSHSHSX 660
            ||||||.|.::||   .|||..||||     ...||  |...|.||.|.   |||.|
Human   352 KKQNPGADTSAPT---GGGGGPGPGAGPGTGLPGGL--SPLSPSPPMGA---PLGMH-------- 400

  Fly   661 NCKMQQRLLQLFEKRGRAVAGGAG-PAAGSGSV 692
                                |.|| ||.|.|.:
Human   401 --------------------GPAGYPAHGPGGL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeobox	549..601	CDD:278475	49/51 (96%)
NKX1-1	NP_001277008.1	Homeobox	300..352	CDD:278475	49/51 (96%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6088
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_109243
Panther	1	1.100	-	-	O	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2564
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.800