Protein Alignment slou and MSX2

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_002440.2
• Gene: MSX2 / 4488
• HGNCID: 7392
• Length: 267
• Species: Homo sapiens
• Alignment Length: 306
• Identity: 85/306 - (27%)
• Similarity: 117/306 - (38%)
• Gaps: 90/306 - (29%)

  Fly   395 GNDEDSNDGSHSTPSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNK-- 457
            |||..|.|  ...|:|.         :.....|..|. .|:.:|......|.||||.::...|
Human     7 GNDLFSPD--EEGPAVV---------AGPGPGPGGAE-GAAEERRVKVSSLPFSVEALMSDKKPP 59

  Fly   458 FTGNKLPS-------------------------GPFGHPRQWSYERDEEMQERLDDDQSEDMSAQ 497
            ...:.||:                         ||...|.:.:..:.|         .|||.:|.
Human    60 KEASPLPAESASAGATLRPLLLSGHGAREAHSPGPLVKPFETASVKSE---------NSEDGAAW 115

  Fly   498 DLNDMDQDDMCDDGSDIDDP---SSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVS 559
                     |.:.|.....|   |..|.:.:....|               |:.||.||..||::
Human   116 ---------MQEPGRYSPPPRHMSPTTCTLRKHKTN---------------RKPRTPFTTSQLLA 156

  Fly   560 LENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKK-QNPGMDVNSPTIPPPGGGSFG 623
            ||.||:..:|||:.||...:.||:||||||||||||||.|.|: |...::.......|....||.
Human   157 LERKFRQKQYLSIAERAEFSSSLNLTETQVKIWFQNRRAKAKRLQEAELEKLKMAAKPMLPSSFS 221

  Fly   624 -PGAYASGL----LYSHAVPY-------PPYGPYFHPL--GAHHLS 655
             |...:|.|    :|..:.|:       ||.|.|..|:  |.:|||
Human   222 LPFPISSPLQAASIYGASYPFHRPVLPIPPVGLYATPVGYGMYHLS 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	33/55 (60%)
MSX2	NP_002440.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..71		19/75 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	116..147		7/45 (16%)
		Homeodomain	143..199	CDD:459649	33/55 (60%)