Protein Alignment slou and NKX1-2

DIOPT Version :9

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001139812.1
• Gene: NKX1-2 / 390010
• HGNCID: 31652
• Length: 310
• Species: Homo sapiens
• Alignment Length: 292
• Identity: 111/292 - (38%)
• Similarity: 140/292 - (47%)
• Gaps: 96/292 - (32%)

  Fly   444 RLAFSVENILDPNKFTGNKLPS-GPFGHPRQWSYERDEEMQERLDDDQSEDMSAQD-LNDMDQDD 506
            :::|||.:||||.|||...||: .|  .||       |..:...:.:..:|.|::| :..::..|
Human    17 KISFSVLDILDPQKFTRAALPAVRP--APR-------EARKSLAEVEAGKDASSRDPVRQLETPD 72

  Fly   507 MCDDGS---------------DIDDP----------------SSETDSKKGGSRNGDGKSGGGGG 540
            ....|:               |.:||                :...|:..|...:|:....||||
Human    73 AAGPGAGQASPLEGSEAEEEEDAEDPRRPRLRERAARLLPGLARSPDAPAGALASGEPCEDGGGG 137

  Fly   541 --------GGS-------------KPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSL 584
                    .||             |||||||||||||||:|||||:.||||||||||||||||||
Human   138 PVRSPPGSPGSPRPRRRRLEPNCAKPRRARTAFTYEQLVALENKFRATRYLSVCERLNLALSLSL 202

  Fly   585 TETQVKIWFQNRRTKWKKQNPGMDVNSPT---IPPPG----------GGSFGP---GAY------ 627
            ||||||||||||||||||||||.|..:..   .|.||          |||.||   ||.
Human   203 TETQVKIWFQNRRTKWKKQNPGADGAAQVGGGAPQPGAAGGGGGGGSGGSPGPPGTGALHFQTFP 267

  Fly   628 ---ASGLLYSHAVPYP--------PYGPYFHP 648
               |:.:|:..|..:|        |:.|:..|
Human   268 SYSAANVLFPSAASFPLTAAAPGSPFAPFLGP 299

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeobox	549..601	CDD:278475	48/51 (94%)
NKX1-2	NP_001139812.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..165		25/137 (18%)
		Homeobox	167..219	CDD:278475	48/51 (94%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	217..260		17/42 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	114	1.000	Domainoid score	I6088
eggNOG	1	0.900	-	-		E1_KOG0488
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0007326
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR24340
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2564
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	7	6.900