Protein Alignment slou and HMX3

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001099044.1
• Gene: HMX3 / 340784
• HGNCID: 5019
• Length: 357
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 116/490 - (23%)
• Similarity: 146/490 - (29%)
• Gaps: 206/490 - (42%)

  Fly   222 PHPHP--------HPHPHPHPSAVFHLRAPSSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAP 278
            |.|.|        .|.|.|.|               ||:|..||.|  ....::.|....||  .
Human     2 PEPGPDAAGTASAQPQPPPPP---------------PPAPKESPFS--IKNLLNGDHHRPPP--K 47

  Fly   279 PQNPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSS 343
            ||.||                              ||..|.:::|.|
Human    48 PQPPP------------------------------RTLFAPASAAAA------------------ 64

  Fly   344 GSPSGRDLSDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTP 408
                                |||||||||......||.:|.|...
Human    65 --------------------AAAAAAAAAKGALEGAAGFALSQVG-------------------- 89

  Fly   409 SVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNK---------LP 464
                                          |.|..|.....:....|..:....         .|
Human    90 ------------------------------DLAFPRFEIPAQRFALPAHYLERSPAWWYPYTLTP 124

  Fly   465 SGPFGH-PRQWSYE----RDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSK 524
            :|  || ||..:.|    ||.......|.|..|.:...|.:..:.|....|...:::..||...|
Human   125 AG--GHLPRPEASEKALLRDSSPASGTDRDSPEPLLKADPDHKELDSKSPDEIILEESDSEESKK 187

  Fly   525 KGGSRNG-DGKSGGGGG----------GGSKP--------RRARTAFTYEQLVSLENKFKTTRYL 570
            :|.:..| .|.|.|...          |...|        ::.||.|:..|:..||:.|...|||
Human   188 EGEAAPGAAGASVGAAAATPGAEDWKKGAESPEKKPACRKKKTRTVFSRSQVFQLESTFDMKRYL 252

  Fly   571 SVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPG-------------MDVNSPTIPPPGGGSF 622
            |..||..||.||.||||||||||||||.|||:|...             ..|..|.:......:.
Human   253 SSSERAGLAASLHLTETQVKIWFQNRRNKWKRQLAAELEAANLSHAAAQRIVRVPILYHENSAAE 317

  Fly   623 GPGAYASG--------LLYSHAVPYPPYGPYFHPL 649
            |..|.|:|        ||   ..|:|.|  |.||:
Human   318 GAAAAAAGAPVPVSQPLL---TFPHPVY--YSHPV 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	33/55 (60%)
HMX3	NP_001099044.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..58		22/104 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	129..229		21/99 (21%)
		Homeodomain	228..284	CDD:459649	33/55 (60%)