Protein Alignment slou and MNX1

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_005506.3
• Gene: MNX1 / 3110
• HGNCID: 4979
• Length: 401
• Species: Homo sapiens
• Alignment Length: 414
• Identity: 94/414 - (22%)
• Similarity: 130/414 - (31%)
• Gaps: 175/414 - (42%)

  Fly   244 SSSSTAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQ---------------------------- 280
            |..::...|||:|  .||.:||   |:..:...:||:
Human    51 SGGTSGSCSPASS--EPPAAPA---DRLRAESPSPPRLLAAHCALLPKPGFLGAGGGGGGTGGGH 110

  Fly   281 -NPPHSSQPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALA---SASNSVSNASISISNS 341
             .|.|.:.|.                  .||.||....|::...||   ....:...|.:....:
Human   111 GGPHHHAHPG------------------AAAAAAAAAAAAAAGGLALGLHPGGAQGGAGLPAQAA 157

  Fly   342 SSGSPSGRDLSDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHS 406
            ..|.|.      ||:        :|||||||.:.|..|.:|:....              .|:|.
Human   158 LYGHPV------YGY--------SAAAAAAALAGQHPALSYSYPQV--------------QGAHP 194

  Fly   407 TPSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHP 471
            .....|:.|             .|.|              |.::..|..:. .|..||..|
Human   195 AHPADPIKL-------------GAGT--------------FQLDQWLRAST-AGMILPKMP---- 227

  Fly   472 RQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSG 536
                                      |.|...|.::.
Human   228 --------------------------DFNSQAQSNLL---------------------------- 238

  Fly   537 GGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK 601
                  .|.||.|||||.:||:.||::||..:|||..:|..:|.||.||||||||||||||.|||
Human   239 ------GKCRRPRTAFTSQQLLELEHQFKLNKYLSRPKRFEVATSLMLTETQVKIWFQNRRMKWK 297

  Fly   602 KQNPGMDVNSPTIPPPGGGSFGPG 625
            :.....:..:.......||..|.|
Human   298 RSKKAKEQAAQEAEKQKGGGGGAG 321

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	36/55 (65%)
MNX1	NP_005506.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	37..78		10/31 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..120		2/18 (11%)
		Homeodomain	242..298	CDD:459649	36/55 (65%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	299..401		4/23 (17%)