Protein Alignment slou and Nkx2-1

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: XP_006240178.1
• Gene: Nkx2-1 / 25628
• RGDID: 3866
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 348
• Identity: 88/348 - (25%)
• Similarity: 124/348 - (35%)
• Gaps: 98/348 - (28%)

  Fly   408 PSVCPVDLTRSVNSSAAANPSSASTSASSDRDAATKRLA-FSVENILDPNKFTGNK--LPSGPFG 469
            ||:....|.|:.::....:|:.::.|.......:.|... |||.:||.|.:.:..|  :..|..|
  Rat    22 PSLHSSQLRRTRSTPLRVHPTRSALSRRRIMSMSPKHTTPFSVSDILSPLEESYKKVGMEGGGLG 86

  Fly   470 HPRQWSYERDE------EMQERLDDDQ-----SEDMSAQDLNDMD-------------------- 503
            .|.. :|.:.:      .||:......     :..|:|..:..:.
  Rat    87 APLA-AYRQGQAAPPAAAMQQHAVGHHGAVTAAYHMTAAGVPQLSHSAVGGYCNGNLGNVSELPP 150

  Fly   504 -QDDMCDDGSD------IDDPSSETDSKKGGSRNGDGKSGGGGGGG------------SKPRR-A 548
             ||.|.:..|.      ..||.....|:..|..:|...||.||.|.            |.||| .
  Rat   151 YQDTMRNSASGPGWYGANPDPRFPAISRFMGPASGMNMSGMGGLGSLGDVSKNMAPLPSAPRRKR 215

  Fly   549 RTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPT 613
            |..|:..|:..||.:||..:|||..||.:||..:.||.|||||||||.|.|.|:|..........
  Rat   216 RVLFSQAQVYELERRFKQQKYLSAPEREHLASMIHLTPTQVKIWFQNHRYKMKRQAKDKAAQQQL 280

  Fly   614 IPPPGGGSFGPGAYASGLLYSHAVPYPPYGPYFHPLGAHHLSHSHSXNCKMQQRLLQ-------- 670
            ....|||..|.|                        ||         .|..||:..|
  Rat   281 QQDSGGGGGGGG------------------------GA---------GCPQQQQAQQQSPRRVAV 312

  Fly   671 -LFEKRGRAVAGGAGPAAGSGSV 692
             :..|.|:....|| ||.|:.|:
  Rat   313 PVLVKDGKPCQAGA-PAPGAASL 334

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	29/56 (52%)
Nkx2-1	XP_006240178.1	Homeodomain	213..269	CDD:459649	28/55 (51%)