Protein Alignment slou and Nkx2-4

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_075993.1
• Gene: Nkx2-4 / 228731
• MGIID: 97349
• Length: 354
• Species: Mus musculus
• Alignment Length: 515
• Identity: 105/515 - (20%)
• Similarity: 136/515 - (26%)
• Gaps: 267/515 - (51%)

  Fly   231 HPHPSAVFHLRAPSSSS---------TAPPSPATSPLSPPTSPAMHSDQQMSPPIAPPQNPPHSS 286
            |..|.:|..:.:|...:         .|||.     |..|...|.:.        |||..|  ||
Mouse     7 HTTPFSVSDILSPIEETYKKFGGVMDGAPPG-----LGAPLGAAAYR--------APPSGP--SS 56

  Fly   287 QPPQQQQVAAPSDMDLERIKLVAAVAARTTQASSTSALASASNSVSNASISISNSSSGSPSGRDL 351
            |                    .|||||......:
Mouse    57 Q--------------------AAAVAAGMQPPHA------------------------------- 70

  Fly   352 SDYGFRIQLGGLAAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSNDGSHSTPSVCPVDLT 416
                    :.|..||||||||.:...|||||                      |..|.|
Mouse    71 --------MAGHNAAAAAAAAAAAAAAAATY----------------------HMPPGV------ 99

  Fly   417 RSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERDEE 481
                                                             ..|.|....||
Mouse   100 -------------------------------------------------SQFPHSAMGSY----- 110

  Fly   482 MQERLDDDQSEDMSAQDLNDMDQDDMCDDG-SDIDDPSSETDSKKGGS---------RNGD---- 532
                                      |:.| .::.:..:.||..:||:         .|.|
Mouse   111 --------------------------CNGGLGNMGELPAYTDGMRGGAAAAATGWYGANTDPRYS 149

  Fly   533 ------GKSGGGGGGG-------------------SKPRR-ARTAFTYEQLVSLENKFKTTRYLS 571
                  |.|.|....|                   :.||| .|..|:..|:..||.:||..:|||
Mouse   150 SISRFMGPSAGVNVAGMGSLTGIADAAKSLAPLHAAAPRRKRRVLFSQAQVYELERRFKQQKYLS 214

  Fly   572 VCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDVNSPTIPPPGGGSFGPGAYASGLLYSHA 636
            ..||.:||..:.||.|||||||||.|.|.|:|  ..|..:..:...||  .||           .
Mouse   215 APEREHLASMIHLTPTQVKIWFQNHRYKMKRQ--AKDKAAQQLQQEGG--LGP-----------P 264

  Fly   637 VPYPPYGPYFHPLGAHHLSHSHSXNCKMQQRLLQLFEKRGRAVAGGAG-PAAGSGSVDPK 695
            .|.||..|                    ::..:.:..|.|:....||| |..|.|...|:
Mouse   265 PPPPPPSP--------------------RRVAVPVLVKDGKPCQNGAGTPTPGQGGQQPQ 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	29/56 (52%)
Nkx2-4	NP_075993.1	Homeodomain	189..245	CDD:459649	28/55 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	245..329		19/95 (20%)