Protein Alignment slou and Nkx2-2

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_035049.1
• Gene: Nkx2-2 / 18088
• MGIID: 97347
• Length: 273
• Species: Mus musculus
• Alignment Length: 282
• Identity: 76/282 - (26%)
• Similarity: 103/282 - (36%)
• Gaps: 99/282 - (35%)

  Fly   444 RLAFSVENILD--------------PNKFTGNKLP---SGPFGHPRQWSYERDEEMQERLDDDQS 491
            :..|||::|||              |.:.:....|   :||.|             |..||..||
Mouse     7 KTGFSVKDILDLPDTNDEDGSVAEGPEEESEGPEPAKRAGPLG-------------QGALDAVQS 58

  Fly   492 EDMSAQDLNDMDQD----------------------DMCDDGSDIDDPSSETDSKKGGSRNGDGK 534
            ..:.:...:..|..                      ...|..|...:||::.      |.:.|.:
Mouse    59 LPLKSPFYDSSDNPYTRWLASTEGLQYSLHGLAASAPPQDSSSKSPEPSADE------SPDNDKE 117

  Fly   535 SGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTK 599
            :.||||...|.|:.|..|:..|...||.:|:..||||..||.:||..:.||.|||||||||.|.|
Mouse   118 TQGGGGDAGKKRKRRVLFSKAQTYELERRFRQQRYLSAPEREHLASLIRLTPTQVKIWFQNHRYK 182

  Fly   600 WK--KQNPGMDVNSPTIPPP-----------------------GGGSFGPG----AYASGLL--- 632
            .|  :...||:|.  .:|.|                       ...:|..|    ||::..|
Mouse   183 MKRARAEKGMEVT--PLPSPRRVAVPVLVRDGKPCHALKAQDLAAATFQAGIPFSAYSAQSLQHM 245

  Fly   633 -----YSHAVPYPPYGPYFHPL 649
                 ||.| ..|.| |..|||
Mouse   246 QYNAQYSSA-STPQY-PTAHPL 265

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	29/57 (51%)
Nkx2-2	NP_035049.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..56		14/61 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	91..131		12/45 (27%)
		Homeodomain	129..185	CDD:459649	28/55 (51%)