Protein Alignment slou and NKX2-3

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_660328.2
• Gene: NKX2-3 / 159296
• HGNCID: 7836
• Length: 364
• Species: Homo sapiens
• Alignment Length: 371
• Identity: 84/371 - (22%)
• Similarity: 115/371 - (30%)
• Gaps: 147/371 - (39%)

  Fly   364 AAAAAAAAATSRQIAAATYARSDTSEELNVDGNDEDSND--------------GSHSTPSVCPVD 414
            :|....|||...|.:               ||.:||..|              ..|....:||..
Human    42 SAPCMLAAAEGTQFS---------------DGGEEDEEDEGEKLSYLNSLAAADGHGDSGLCPQG 91

  Fly   415 LTRSVNSSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPSGPFGHPRQWSYERD 479
            ...:|...:.:.|.                                                |.:
Human    92 YVHTVLRDSCSEPK------------------------------------------------EHE 108

  Fly   480 EEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSK 544
            ||.:...|..|.   |.|....::....|       ..:.|::..|..||
Human   109 EEPEVVRDRSQK---SCQLKKSLETAGDC-------KAAEESERPKPRSR--------------- 148

  Fly   545 PRRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWK--KQNPGM 607
             |:.|..|:..|:..||.:||..||||..||.:||.||.||.|||||||||||.|.|  :|:..:
Human   149 -RKPRVLFSQAQVFELERRFKQQRYLSAPEREHLASSLKLTSTQVKIWFQNRRYKCKRQRQDKSL 212

  Fly   608 DVNSPTIPPP------------GGGSFGPGAYASGLLYSHAV------PYPPYGPYFH------- 647
            ::.:...|||            |.....|.|.|.|..||...      .:|.|| |.:
Human   213 ELGAHAPPPPPRRVAVPVLVRDGKPCVTPSAQAYGAPYSVGASAYSYNSFPAYG-YGNSAAAAAA 276

  Fly   648 --PLGAHHLSHSHSXNCKMQQRLLQLFEKRGRAVAGGAGPAAGSGS 691
              ...|...::|.|..|...              |||.|...|:.:
Human   277 AAAAAAAAAAYSSSYGCAYP--------------AGGGGGGGGTSA 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	33/57 (58%)
NKX2-3	NP_660328.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	132..153		6/43 (14%)
		Homeodomain	149..205	CDD:459649	32/55 (58%)