Protein Alignment slou and Hhex

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_032271.1
• Gene: Hhex / 15242
• MGIID: 96086
• Length: 271
• Species: Mus musculus
• Alignment Length: 234
• Identity: 61/234 - (26%)
• Similarity: 76/234 - (32%)
• Gaps: 92/234 - (39%)

  Fly   404 SHSTP------------SVCPVDLTRSVNSSAAANPSSAST---------SASSDRDAATKRLAF 447
            :|.||            :..|.....|.|||..:..||..|         .|.|...||....|:
Mouse    28 AHPTPFYIDDILGRGPAAPTPTPTLPSPNSSFTSLVSSYRTPVYEPTPVHPAFSHHPAAALAAAY 92

  Fly   448 SVENILDP--------NKFTGNKLPSGPFGHPRQWSYERDEEMQERLDDDQSEDMSAQDLNDMDQ 504
            .......|        |.:|...|...|.|.|..||......:.:|
Mouse    93 GPSGFGGPLYPFPRTVNDYTHALLRHDPLGKPLLWSPFLQRPLHKR------------------- 138

  Fly   505 DDMCDDGSDIDDPSSETDSKKGGSRNGDGKSGGGGGGGSKPRRARTAFTYEQLVSLENKFKTTRY 569
                                |||                     :..|:.:|.|.||.||:|.:|
Mouse   139 --------------------KGG---------------------QVRFSNDQTVELEKKFETQKY 162

  Fly   570 LSVCERLNLALSLSLTETQVKIWFQNRRTKW---KKQNP 605
            ||..||..||..|.|:|.|||.||||||.||   |::||
Mouse   163 LSPPERKRLAKMLQLSERQVKTWFQNRRAKWRRLKQENP 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	29/58 (50%)
Hhex	NP_032271.1	Interaction with SOX13. /evidence=ECO:0000250|UniProtKB:Q03014	1..138		25/109 (23%)
		Required for WNT signaling induction. /evidence=ECO:0000250|UniProtKB:Q03014	138..271		36/124 (29%)
		Homeodomain	143..195	CDD:459649	29/51 (57%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	195..271		3/7 (43%)