Protein Alignment slou and NKX2-6

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_001129743.2
• Gene: NKX2-6 / 137814
• HGNCID: 32940
• Length: 301
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 89/305 - (29%)
• Similarity: 116/305 - (38%)
• Gaps: 97/305 - (31%)

  Fly   447 FSVENILDPNKFTGNKLPSGPFGHPR------QWSYER-DEEMQ-------------ERLDDDQS 491
            |||::||   :....:.......|||      .:.|.| |.|.:             .:||..:.
Human    11 FSVKDIL---RLERERSCPAASPHPRVRKSPENFQYLRMDAEPRGSEVHNAGGGGGDRKLDGSEP 72

  Fly   492 EDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGS----RNGDGKSGGG--GGGGSKP----- 545
            .....:.:.:||.:.|.:     ..|.....|..||.    ..|.|.||..  ||...:|
Human    73 PGGPCEAVLEMDAERMGE-----PQPGLNAASPLGGGTRVPERGVGNSGDSVRGGRSEQPKARQR 132

  Fly   546 RRARTAFTYEQLVSLENKFKTTRYLSVCERLNLALSLSLTETQVKIWFQNRRTKWKKQNPGMDV- 609
            |:.|..|:..|:::||.:||..||||..||.:||.:|.||.|||||||||||.|.|:|.....:
Human   133 RKPRVLFSQAQVLALERRFKQQRYLSAPEREHLASALQLTSTQVKIWFQNRRYKCKRQRQDKSLE 197

  Fly   610 -------------------NSPTIPPPGGGSFGPGAYASGLLYSHAV-PYPPYGPYF-HPLGAHH 653
                               ..|.:.|      ||||.|....||.|| ||..||.|. .|.||.:
Human   198 LAGHPLTPRRVAVPVLVRDGKPCLGP------GPGAPAFPSPYSAAVSPYSCYGGYSGAPYGAGY 256

  Fly   654 LSHSHSXNCKMQQRLLQLFEKRGRAVAGG-AGPA-------AGSG 690
                                  |...||. :|||       ||.|
Human   257 ----------------------GTCYAGAPSGPAPHTPLASAGFG 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	31/55 (56%)
NKX2-6	NP_001129743.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	22..135		24/117 (21%)
		Homeodomain	133..189	CDD:459649	31/55 (56%)