Protein Alignment slou and CDX4

DIOPT Version :10

• Sequence 1: NP_001262808.1
• Gene: slou / 42547
• FlyBaseID: FBgn0002941
• Length: 698
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 254
• Identity: 61/254 - (24%)
• Similarity: 94/254 - (37%)
• Gaps: 78/254 - (30%)

  Fly   421 SSAAANPSSASTSASSDRDAATKRLAFSVENILDPNKFTGNKLPS-----GPFGHPRQ-WSYERD 479
            :....:|..||..|::  .|.:..:.:.....:||:      .||     .|:..||: ||
Human    32 TGGGGSPMPASNFAAA--PAFSHYMGYPHMPSMDPH------WPSLGVWGSPYSPPREDWS---- 84

  Fly   480 EEMQERLDDDQSEDMSAQDLNDMDQDDMCDDGSDIDDPSSETDSKKGGSRNGD---GKSGG---- 537
                  :....|..|....:||:.........:|..:.     ...||..:|.   |::||
Human    85 ------VYPGPSSTMGTVPVNDVTSSPAAFCSTDYSNL-----GPVGGGTSGSSLPGQAGGSLVP 138

  Fly   538 ---GGGGGSKPRRA------------------------RTAFTYEQLVSLENKFKTTRYLSVCER 575
               |....|.|.|:                        |..:|..|.:.||.:|...||:::..:
Human   139 TDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRTKEKYRVVYTDHQRLELEKEFHCNRYITIQRK 203

  Fly   576 LNLALSLSLTETQVKIWFQNRRTKWKK---------QNPGMDVNSPTIPPPGGGSFGPG 625
            ..||::|.|:|.||||||||||.|.:|         :|.|..|.|.:      .|..||
Human   204 SELAVNLGLSERQVKIWFQNRRAKERKMIKKKISQFENSGGSVQSDS------DSISPG 256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
slou	NP_001262808.1	Homeodomain	546..602	CDD:459649	25/79 (32%)
CDX4	NP_005184.1	Caudal_act	13..170	CDD:461413	29/160 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		1/7 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		10/34 (29%)
		Homeodomain	175..230	CDD:459649	24/54 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		7/25 (28%)