DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7956 and SAC1

DIOPT Version :9

Sequence 1:	NP_001036740.2	Gene:	CG7956 / 42545	FlyBaseID:	FBgn0038890	Length:	1142	Species:	Drosophila melanogaster
Sequence 2:	NP_012710.1	Gene:	SAC1 / 853668	SGDID:	S000001695	Length:	623	Species:	Saccharomyces cerevisiae

Alignment Length:	445	Identity:	170/445 - (38%)
Similarity:	238/445 - (53%)	Gaps:	52/445 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   158 NTIKNTTQ----------QAANLATKQVKSSVGIREPRHIERRITEELHKIFDETDSFYFSFDCD 212
            ||::.|.:          |.:.::|| ..|.:...|..:|:   ..|||.   :..:||||:..|
Yeast    74 NTVEETGRFNGHVFYRVLQHSIVSTK-FNSRIDSEEAEYIK---LLELHL---KNSTFYFSYTYD 131

  Fly   213 ITNNLQRHE-AKSEESQSQPDERFFWNKHMIRDLINLNDK-----TWILPIIQGFMQVENCVIGN 271
            :||:|||:| .....|....|||||||.::..||.|...:     ::|.|:|.|:.:..:.|:..
Yeast   132 LTNSLQRNEKVGPAASWKTADERFFWNHYLTEDLRNFAHQDPRIDSFIQPVIYGYAKTVDAVLNA 196

  Fly   272 ECFTLALVSRRSRHRAGTRYKRRGVDEKGNCANYVETEQIL------SFRHHQLSFTQVRGSVPI 330
            ....|.|::|||..||||||.|||||:.||..|:.||||||      |.:.|..||.|.||||||
Yeast   197 TPIVLGLITRRSIFRAGTRYFRRGVDKDGNVGNFNETEQILLAENPESEKIHVFSFLQTRGSVPI 261

  Fly   331 YWSQ-PGYKYRPPPRLDRGVAETQQAFELHFTKELETYGRVCIVNLVEQSGKEKTIGDAYADHVI 394
            ||:: ...||:|...|..   .:..|.:.||.::.|.||...:||||.|.|.|..:.:.|...|.
Yeast   262 YWAEINNLKYKPNLVLGE---NSLDATKKHFDQQKELYGDNYLVNLVNQKGHELPVKEGYESVVH 323

  Fly   395 KLNNDRLIYVTFDFHDYCRGMRFENVSALIDAVGPEAGAMG---FH-WRDQRG----MICNQKSV 451
            .||:.::.||.||||..||.|::..|..|||.: .:.|...   || ..|..|    ::..|.||
Yeast   324 ALNDPKIHYVYFDFHHECRKMQWHRVKLLIDHL-EKLGLSNEDFFHKVIDSNGNTVEIVNEQHSV 387

  Fly   452 FRVNCMDCLDRTNVVQTAIGKAVLESQ-----LVKLGLS-PPYTPIPEQLKSPFMVLWANNGDII 510
            .|.|||||||||||||:.:.:.||:.:     :|..|.: ....|    |.:.:..|||:|.|.:
Yeast   388 VRTNCMDCLDRTNVVQSVLAQWVLQKEFESADVVATGSTWEDNAP----LLTSYQNLWADNADAV 448

  Fly   511 SRQYAGTNALKGDYTRTGERKISGMMKDGMNSANRFFIQNFADSFRQCIIDLMQG 565
            |..|:||.|||.|:||||:|...|...|.:|||:|::..|:.|..||...||..|
Yeast   449 SVAYSGTGALKTDFTRTGKRTRLGAFNDFLNSASRYYQNNWTDGPRQDSYDLFLG 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7956	NP_001036740.2	Syja_N	174..413	CDD:280532	98/251 (39%)
		COG5329	<197..586	CDD:227637	158/396 (40%)
		hSac2	663..768	CDD:289241
SAC1	NP_012710.1	COG5329	3..578	CDD:227637	170/445 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910